【摘要】 目的 研究点阵式二氧化碳激光治疗外阴阴道口萎缩的外阴色素减退性疾病患者的疗效及可行性。方法 回顾性选取2021年2月至2022年4月期间郑州大学第三附属医院妇科门诊就诊的具有外阴阴道口萎缩症状的患者43例，观察组23例患者采用点阵式二氧化碳激光治疗仪进行外阴及阴道口治疗3次，对照组20例患者采用外阴和阴道内使用普罗雌烯胶囊。于治疗前、治疗后3个月及6个月采用皮肤病生活质量指数（Dermatology Life Quality Index,DLQI）评分、女性性苦恼量表（female sexual distress scale-revised,FSDS-R）及女性性功能指数（Female Sexual Function Index, FSFI）量表评估患者的症状和性生活状况，并进行满意度调查。结果 治疗后3个月，观察组DLQI、FSDS-R和FSFI评分均较治疗前有改善（P <0.05），对照组FSDS-R和FSFI评分均有改善（P<0.05），观察组患者改善效果优于对照组（P<0.05）。治疗后6个月，观察组DLQI、FSDS-R和FSFI评分均较治疗前有改善（P<0.05），对照组评分无明显改善（P> 0.05）。结论 点阵式二氧化碳激光治疗能够改善外阴阴道口萎缩的外阴色素减退性疾病患者症状，疗效确切。更多还原

【Abstract】 Objective To explore the efficacy and feasibility of fractional carbon dioxide laser treatment for patients with hypopigmented vulvar disease with vulvar-vaginal orifice atrophy. Methods A total of forty-three patients with symptoms of vulvarvaginal orifice atrophy treated in the Third affiliated Hospital of Zhengzhou University from February 2021 to April 2022 are selected and followed up successfully. 23 patients in the observation group are treated with carbon dioxide laser therapy for three times for vulvar and vaginal orifices, while 20 patients in the control group are treated with vulvar and intravaginal use of promestriene vaginal capsules. The changes of Dermatology Life Quality Index(DLQI), female sexual distress scale-revised(FSDS-R) and Female Sexual Function Index(FSFI) are observed before, 3 months and 6 months after treatment. Result Three months after treatment, the DLQI,FSDS-R and FSFI scores in the observation group are significantly improved compared with those before treatment(P < 0.05), and the FSDS-R and FSFI scores in the control group are relatively improved(P < 0.05), and the improvement in the observation group is superior to that in the control group(P < 0.05). The DLQI, FSDS-R and FSFI scores are significantly improved in the observation group at 6 months after treatment(P < 0.05), and there is no difference between the scores in the control group before treatment(P > 0.05).Conclusion Carbon dioxide fractional laser treatment can significantly improve the symptoms of patients with hypopigmented vulvar disease with vulvovaginal orifice atrophy.更多还原