【摘要】 报道了一种多取代喹啉/吡咯杂环化合物的电化学合成新方法.反应以亚硝基苯和贫电子内炔为起始物,在无需额外金属催化剂、室温条件下,通过阴极单电子还原的策略,选择性地还原亚硝基苯产生亚硝基自由基,随后与炔烃进行串联环化反应,绿色、高效地合成了一系列具有高附加值的多取代喹啉/吡咯杂环化合物.更多还原

【Abstract】 A novel electrochemical cascade cyclization between nitrosobenzene and electron-deficient alkynes was developed in this work. The use of electroreduction for the activation of nitrosobenzene which highlighted the unique possibilities associated with electrochemical activation methods. This protocol represents a simple, efficient, and environmentally benign way to construct substituted quinolines and pyrroles in good yields with high selectivity.更多还原