【摘要】 目的:系统评价预康复对腹腔镜胆囊切除术(LC)病人术后恢复的影响。方法:计算机检索中国知网、维普数据库、中国生物医学文献数据库、万方数据库、PubMed、EMbase、Web of Science和the Cochrane Library中关于预康复应用于LC病人的随机对照研究、队列研究、病例对照研究，检索时限从建库至2023年6月4日；使用RevMan 5.4软件对纳入研究进行Meta分析。结果:共纳入6篇文献，涉及501例LC病人。Meta分析结果显示，预康复对LC病人术后并发症发生率[RR=0.50,95%CI(0.33,0.76),P=0.001]、术后焦虑评分[SMD=-1.04,95%CI(-1.31,-0.77),P<0.000 01]、术后抑郁评分[SMD=-1.04,95%CI(-1.38,-0.71),P<0.000 01]、住院时间[MD=-0.41,95%CI(-0.64,-0.18),P=0.000 5]、术后首次下床活动时间[SMD=-0.43,95%CI(-0.66,-0.19),P=0.000 5]、术后6MWD[MD=47.44,95%CI(38.19,56.69),P<0.000 01]的干预效果均优于对照组；两组术后首次肛门排气时间比较，差异无统计学意义(P>0.05)。结论:现有证据表明，预康复能降低LC病人术后并发症发生率，改善焦虑、抑郁情绪，缩短住院时间、术后首次下床活动时间；但对于术后首次肛门排气时间及6MWD的干预效果尚存争议。更多还原

【Abstract】 Objective:To systematically evaluate the impact of pre-rehabilitation on postoperative recovery in patients undergoing laparoscopic cholecystectomy(LC).Methods:Computer retrieval of studies on the application of pre-rehabilitation to LC patients from CNKI,VIP,CBM,WanFang Database, PubMed, EMbase, Web of Science, and the Cochrane Library.The retrieval time was from the inception to June 4,2023.Meta-analysis was conducted on the included studies using RevMan 5.4 software.Results:A total of 6 articles were included, including 501 LC patients.Meta-analysis results showed that pre-rehabilitation had an impact on the incidence of postoperative complications in LC patients(RR=0.50,95%CI 0.33-0.76,P=0.001),postoperative anxiety score(SMD=―1.04,95%CI ―1.31-―0.77,P<0.000 01),postoperative depression score(SMD=―1.04,95%CI ―1.38-―0.71,P<0.000 01),length of hospital stay(MD=―0.41,95%CI ―0.64-―0.18,P=0.000 5),postoperative first time of getting out of bed(SMD=―0.43,95%CI ―0.66-―0.19,P=0.000 5),postoperative 6MWD[MD=47.44,95%(38.19,56.69),P<0.000 01]were better than the control group.There was no statistically significant difference in the first postoperative anal exhaust time between the two groups(P>0.05).Conclusion:Current evidence suggests that pre-rehabilitation can reduce the incidence of postoperative complications in LC patients, improve anxiety and depression, shorten hospital stay, and shorten the first time out of bed activity after surgery.However, there is still controversy over the intervention effect of postoperative first anal exhaust time.更多还原