【摘要】 肥胖所引发的神经毒性使得脑结构和脑网络发生改变，从而导致肥胖者的认知功能减退，进而阻碍身体机能的恢复，因此肥胖可能是一个关于身体和大脑的复合体疾病。相关研究发现，肥胖者脑网络的改变可能是导致肥胖伴认知障碍的主要原因。该文简要阐述了肥胖与脑网络改变的中介和调节因素，并探讨了肥胖者脑功能网络的异常机制，为筛查、预防、治疗和监测肥胖合并认知损害提供新策略。更多还原

【Abstract】 The neurotoxicity caused by obesity leads to changes in brain structure and network, resulting in cognitive decline in obese individuals and hindering the recovery of bodily functions.Therefore, obesity may be a complex disease related to the body and brain.Related studies have found that changes in the brain network of obese individuals may be the main cause of cognitive impairment associated with obesity.The article briefly elaborates on the mediating and regulatory factors between obesity and changes in brain networks, and explores the abnormal mechanisms of brain functional networks in obese individuals, providing new strategies for screening, preventing, treating, and monitoring obesity combined with cognitive impairment.更多还原