【摘要】 脓毒症是由宿主对感染的反应失调而引起的危及生命的器官功能障碍。脓毒症心肌病作为脓毒症最严重的并发症,其发生发展与心肌线粒体功能损伤密切相关。本文将就线粒体结构、线粒体质量控制体系、线粒体功能改变与脓毒症心肌病之间的联系进行综述,为脓毒症心肌病的诊断及治疗提供新的策略。更多还原

【Abstract】 Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to the infection. As the most severe complication of sepsis, the occurrence and development of sepsis-induced cardiomyopathy are closely related to the myocardial mitochondrial function injury. This article explores the relationships between mitochondrial structure, mitochondrial quality control system, mitochondrial function changes and septic cardiomyopathy, aiming to provide new strategies for diagnosis and treatment of septic cardiomyopathy.更多还原