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特发性正常压力脑积水的诊疗进展

Progress in diagnosis and treatment of idiopathic normal pressure hydrocephalus

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【作者】 贺教江李歆晨王珊周良学

【Author】 HE Jiaojiang;LI Xinchen;WANG Shan;ZHOU Liangxue;Department of Neurosurgery, West China Hospital, Sichuan University;

【机构】 四川大学华西医院神经外科

【摘要】 特发性正常压力脑积水(iNPH)多见于老年人,以步态障碍、认知障碍和尿失禁三联征为特征,与脑室扩大有关但脑脊液压力正常。早期诊断识别通过脑脊液分流手术可以有效改善症状,但由于诊断复杂,临床易漏诊和误诊。近二十年来,iNPH的诊断和治疗方式不断更新和改善,促进了规范诊疗,有利于提高患者的生活质量。本文对iNPH的流行病学、诊断和治疗现状以及新发现、新观点作一述评,旨在为临床医师诊疗iNPH患者提供参考和借鉴。

【Abstract】 Idiopathic normal pressure hydrocephalus(iNPH), which is frequently seen in the elderly, is characterized by the triad of gait disturbance, cognitive impairment and urinary incontinence, and is associated with ventricular enlargement but normal cerebrospinal fluid pressure. Early diagnosis and identification can effectively improve symptoms through cerebrospinal fluid shunt surgery. However, due to the complexity of diagnosis, iNPH is easily missed and misdiagnosed clinically. In the past two decades, the diagnosis and treatment methods of iNPH have been continuously updated and improved, promoting standard diagnosis and treatment and helping to improve the quality of life of patients. Aiming to provide clinical reference for the diagnosis and treatment of iNPH, this article reviews the epidemiology, diagnosis and treatment status of it, as well as new findings and perspectives.

【基金】 国家自然科学基金青年项目(82201502)
  • 【文献出处】 西部医学 ,Medical Journal of West China , 编辑部邮箱 ,2024年06期
  • 【分类号】R742.7
  • 【下载频次】58
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