【摘要】 目的 分析深圳市2013-2023年登革热流行病学特征和规律，为制订综合防控措施提供依据。方法 根据中国疾病预防控制信息系统和深圳市登革热疫情现场流行病学调查资料，运用描述性流行病学方法对登革热病例三间分布特征、病例感染地、发病至确诊时间、疫情暴发情况以及病原监测结果进行分析。结果 2013-2023年深圳市累计报告登革热病例1774例，其中本地病例955例，境外输入病例564例，境内输入病例255例。2014年(454例)、2019年(523例)和2023年(386例)是3个疫情高发年份，其中2014年和2023年以本地病例为主，2019年以境外输入病例为主。病例主要集中在8-11月份(占83.8%)。深圳市10个行政区均有病例发生，涉及范围占全市街道总数的94.6%。病例平均年龄为(38.2±13.6)岁，主要集中在20～<50岁年龄段；男女比例为1.9∶1；病例职业大多数为工人、家务及待业人员和商务人员(874/1774，49.3%)。境外输入病例主要来自东南亚国家(478/564,84.8%)，境内输入病例主要来自珠三角地区(157/255，61.6%)。病例发病-诊断中位时间间隔为4.7(2.6，6.8)d，2016-2023年呈现逐年下降趋势，尤其是本地病例。本地暴发疫情24起，主要发生在建筑工地(12起)，10月发生最多(11起)。病例血清型以Ⅰ型登革病毒为主(937/1075，87.2%)。结论 深圳市登革热流行传播风险较大，本地病例主要由输入病例引起，具有明显的时空聚集性。更多还原

【Abstract】 Objective To analyze the epidemiological characteristics of dengue fever in Shenzhen from 2013 to 2023 so as to provide the basis for formulating comprehensive prevention and control measures.Method According to the data from the Chinese Disease Prevention and Control Information System and the epidemiological investigation of dengue fever in Shenzhen,Guangdong Province,descriptive epidemiological methods were applied to analyze the distribution characteristics of the cases,the place of infection,the time from onset to diagnosis,the outbreak situation and the results of pathogen surveillance.Result From 2013 to 2023,a total of 1774 cases of dengue fever were reported in Shenzhen,including 955 local cases,564 imported cases from abroad and 255 imported cases from China.2014 (454 cases),2019 (523 cases) and 2023 (386 cases) were the three high incidence years,among which 2014 and 2023 were dominated by local cases,and 2019 was dominated by imported cases.The cases were mainly concentrated from August to November (83.8%).Cases occurred in 10 administrative districts of Shenzhen,covering 94.6% of the total number of streets in the city.The mean age of the patients was 38.2±13.6 years,mainly in the age group of 20-<50 years.The male to female ratio was 1.9 to 1;Most of the cases were workers,domestic workers,unemployed people and business people,accounting for 49.3% (874/1774).Overseas imported cases were mainly from Southeast Asian countries (478/564,84.8%),and domestic imported cases were mainly from the Pearl River Delta region (157/255,61.6%).The median interval between the onset time and diagnosis time of cases was 4.7 (2.6,6.8) days,and the interval showed a decreasing trend from 2016 to 2023,especially for local cases.There were 24 local outbreaks,mainly at construction sites (12),with the most occurring in October (11).There were a variety of dengue virus serotypes,and type Ⅰ was the dominant type,accounting for 87.2% (937/1075).Conclusion The risk of dengue epidemic transmission in Shenzhen was high,and the local cases were mainly caused by imported cases.It has obvious spatiotemporal aggregation.更多还原