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基于微波透射法的无创型血糖检测技术研究

Research on Non-invasive Blood Glucose DetectionTechnology Based on Microwave Transmission Method

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【作者】 郭凌寒; 任武; 李伟明; 田海燕;

【Author】 GUO Linghan;REN Wu;LI Weiming;TIAN Haiyan;School of Integrated Circuits and Electronics, Beijing Institute of Technology;

【机构】 北京理工大学集成电路与电子学院;

【摘要】 本文结合生物组织的Debye模型参数在电磁仿真软件中建立三维层状耳垂模型,并提出了一种利用不同血糖浓度引起相位的参数变化来评估血液中葡萄糖浓度的方法。利用设计的超宽带贴片天线,对不同血糖浓度、血液量及血液分布的耳垂模型进行仿真研究,观察不同模型对应接收信号的时频域幅度、S21幅度及相位间的差异和规律。结果表明在4GHz-4.4GHz的频段上观测到S21相位与耳垂电磁模型的血糖浓度呈现高度的线性正相关,可以用来评估血液中葡萄糖浓度的方法,为无创型血糖检测技术提供了新的思路。

【Abstract】 In this paper, a 3D laminar earlobe model is built in electromagnetic simulation software by combining the parameters of the Debye model of biological tissues, and a method is proposed to assess the glucose concentration in the blood by using the parameter changes of the phase caused by different blood glucose concentrations. Using the designed ultra-wideband patch antenna, the earlobe model with different glucose concentration, blood volume and blood distribution is simulated and investigated, and the differences and patterns between the time-frequency domain amplitude, S21 amplitude and phase of the received signals corresponding to different models are observed. The results show that the S21 phase observed in the frequency band of 4 GHz to 4.4 GHz shows a highly linear positive correlation with the blood glucose concentration of the earlobe electromagnetic model, which is just the right method to assess the glucose concentration in blood and provides a new idea for non-invasive blood glucose detection technology.

  • 【文献出处】 微波学报 ,Journal of Microwaves , 编辑部邮箱 ,2024年S1期
  • 【分类号】R318;TN820;O441
  • 【下载频次】66
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