【摘要】 维生素K2（vitamin K2,VK₂）是一种长期被忽视的维生素。最近越来越多的证据表明，除了止血相关蛋白的肝脏羧化作用外，VK₂可以在抗氧化、心血管、骨代谢等方面发挥重要作用，而这些作用与妊娠密切相关。由于其可能的缺乏状态以及良好的安全性，最近已经有部分孕妇使用的钙补充剂和综合维生素产品中被添加了VK₂这一成分。然而，据我们所知，目前医学文献中没有针对VK₂和妊娠之间关系的综述。本文旨在介绍VK₂在妊娠期的来源及代谢特点，阐述与妊娠期特有疾病可能的关系，评估妊娠期女性补充VK₂的安全性，以期为妊娠期VK₂补充剂的使用提供合理建议。更多还原

【Abstract】 Vitamin K₂（VK₂） is a vitamin that has been neglected for a long time. Recently, more and more evidences show that, in addition to the hepatic carboxylation of hemostatic related proteins, VK₂ can play an important role in antioxidant, cardiovascular, bone metabolism and so on, which are closely related to pregnancy. Due to its possible deficiency status and good safety, VK₂ has been added to some calcium supplements and multivitamin products used by pregnant women recently. However, to our knowledge, there is no review on the relationship between VK₂ and pregnancy in the medical literature. This article aims to introduce the source and metabolic characteristics of VK₂ in pregnancy, elaborate the possible relationship with pregnancy-specific diseases, evaluate the safety of supplementing VK₂ in pregnant women, in order to provide reasonable suggestions for the use of VK₂ supplements in pregnancy.更多还原