【摘要】 目的 分析2009—2023年福建省登革热发病趋势和流行特征，探索高发人群和热点区域，为制定针对性防控措施提供科学依据。方法 从中国疾病预防控制信息系统收集2009—2023年福建省登革热监测资料，采用描述性流行病学方法进行分析，并对各县（区）发病率进行空间自相关分析。结果 2009—2023年福建省登革热共报告发病3 586例，年均发病率为0.61/10万，疫情总体呈逐年上升趋势（Z=18.35,P<0.001）。其中本地病例2 362例、输入病例1 224例，本地/输入比为1.93∶1（2 362∶1 224）。本地病例主要分布在福州市、莆田市和南平市，合计占87.81%（2 074/2 362）；输入病例主要分布在泉州市、福州市和厦门市，合计占72.55%（888/1 224）。本地/输入比，福州市、南平市和莆田市分别为6.20∶1（1 557∶251）、3.92∶1（145∶37）、3.32∶1（372∶112），均高于全省平均水平。本地疫情空间分布呈聚类模式，有12个发病热点区域，均为福州市所辖县区。发病具有明显季节性：境外输入以7—9月（占45.73%,519/1 135）为主，省外输入以8—11月（占93.25%,83/89）为主，本地病例以8—10月（占97.50%,2 303/2 362）为主。本地病例男女性别比0.88∶1，输入病例3.04∶1；本地病例发病年龄M(P₂₅,P₇₅)为48（32,62）岁，输入病例发病年龄M(P₂₅,P₇₅)为35（28,44）岁。结论 2009—2023年福建省登革热疫情呈持续上升态势，发病存在时空聚集性，应在高发季节针对重点地区和人群加强防控措施。更多还原

【Abstract】 Objective To analyze the incidence trend and epidemiological characteristics of dengue fever in Fujian Province from 2009 to 2023, identify the high-incidence population and hotspot areas, and a scientific basis for formulatingtargeted prevention and control measures.Methods The surveillance data of dengue fever during 2009-2023 in FujianProvince were obtained from the National Disease Reporting Information System and analyzed using descriptiveepidemiological methods, and the spatial autocorrelation analysis of dengue fever incidence at county/district levels was performed with Arc Gl S 10.8.ResultsA total of 3 586 cases of dengue fever were reported in Fujian Province from 2009 to2023, with an average annual incidence rate of 0.61/100 000, showing an overall increasing trend year by year（Z=18.35, P<0.001）. Among them, there were 2 362 local cases and 1 224 imported cases, with a local/imported ratio of 1.93∶1（2 362/1 224）. The local cases were mainly distributed in Fuzhou, Putian, and Nanping, accounting for 87.81%（2 074/2 362）. Theimported cases were mainly distributed in Quanzhou, Fuzhou, and Xiamen, accounting for 72.55%（888/1 224）. The local/imported ratio in Fuzhou, Nanping, and Putian was 6.20∶1（1 557/251）, 3.92∶1（145/37）, and 3.32∶1（372/112）, respectively,all significantly higher than the provincial average level. The spatial distribution of the local cases showed a clustered pattern,with 12 hotspots of incidence, all located in the counties and districts under the jurisdiction of Fuzhou. The onset of the diseasehad obvious seasonality: imported cases from other countries or regions mainly occurred from July to September（accounting for 45.73%, 519/1 135）, imported cases from other provinces mainly occurred from August to November（accounting for 93.25%,83/89）, and local cases mainly occurred from August to October（accounting for 97.50%, 2 303/2 362）. The gender ratio forlocal cases was 0.88∶1, and for imported cases, it was 3.04∶1. The average age of onset for local cases was 48 years old（Q₁=32years old, Q₃=62 years old）, while the average age for imported cases was 35 years old（Q₁=28 years old, Q₃=44 years old）.ConclusionsFrom 2009 to 2023, the dengue fever epidemic in Fujian Province showed a continuous upward trend, withspatiotemporal clustering of incidence. Therefore, prevention and control measures should be strengthened in key areas andpopulations during the high-incidence season.更多还原