【摘要】 氟喹诺酮类(fluoroquinolones, FQs)药物是人类医药与畜禽养殖中最常用的抗生素之一，因其用量大，在环境中广泛残留，对人类和动物健康构成潜在威胁。微生物降解是现阶段消除环境中FQs的理想方式，具有高效、绿色、成本低的特点。目前，关于微生物降解FQs的研究主要集中于降解微生物的筛选和降解产物的鉴定上。本文综述了降解FQs的细菌、真菌、微藻以及微生物降解聚生体的功能特征，并总结了常见降解途径与关键酶。本文为缓解FQs的环境残留问题提供理论基础。更多还原

【Abstract】 Fluoroquinolones(FQs) are one of the most commonly used antibiotics for human medicine and animal breeding. Due to their large dosage, FQs are widely retained in the environment, posing potential threat to human and animal health. Microbial degradation is an ideal way to eliminate FQs in the environment at this stage, which has the characteristics of high efficiency, green and low cost. At present, the research on microbial degradation of FQs mainly focuses on the screening of degradable microorganisms and the identification of degradation products. This paper reviewed the functional characteristics of FQs degradation of bacteria, fungi, microalgae and microorganisms, and summarized the common degradation pathways and key enzymes. This review provides a theoretical basis for alleviating the environmental residue problem of FQs.更多还原