【摘要】 目的:探讨穴位贴敷联合盐酸西替利嗪滴剂及糠酸莫米松鼻喷雾剂治疗儿童变应性鼻炎的临床疗效。方法:将240例变应性鼻炎患儿按照治疗方式不同分为对照组及观察组，每组各120例。对照组采用盐酸西替利嗪滴剂及糠酸莫米松鼻喷雾剂治疗；观察组在对照组的基础上加用穴位贴敷治疗，两组均连续治疗1个月。记录并比较两组患儿中医证候积分、临床疗效、免疫功能、生活质量、不良反应发生情况及家属满意度。结果:治疗后，两组患儿鼻塞、清水样涕、鼻痒、打喷嚏及中医症候积分总分水平均较治疗前降低，且观察组低于对照组(P<0.05)。观察组治疗有效率高于对照组(P<0.05)。治疗后，两组患儿血清白细胞介素4(IL-4)、IL-6及免疫球蛋白E(IgE)水平均较治疗前降低，且观察组低于对照组(P<0.05)。治疗后，两组患儿儿童变应性鼻炎相关生活质量量表(RQLQ)评分均较治疗前降低，且观察组低于对照组(P<0.05)。两组患儿不良反应发生率差异无统计学意义(P>0.05)。观察组患儿家属满意度高于对照组(P<0.05)。结论:穴位贴敷联合盐酸西替利嗪滴剂及糠酸莫米松鼻喷雾剂治疗儿童变应性鼻炎的临床疗效较好，可调节患儿免疫功能，并改善各项临床病症，利于提高生活质量，安全性较高。更多还原

【Abstract】 Objective:To investigate the clinical efficacy of acupoint compresses combined with Cetirizine Dihydrochloride Oral drops and mometasone furoate spray in the treatment of allergic rhinitis in children.Methods:A total of 240 children with allergic rhinitis were selected and divided into a control group and an observation group according to different treatment methods, with 120 cases in each.The control group was treated with Cetirizine Dihydrochloride Oral drops and mometasone furoate spray, and the observation group was treated with acupoint patch on the basis of the control group, with continuous treatment for 1 month.The TCM evidence points, clinical efficacy, immune function, quality of life, adverse reactions and parental satisfaction were recorded and compared between the two groups of children.Results:After treatment, the levels of nasal congestion, clear watery runny nose, nasal itching, sneezing and the total score of Chinese medicine symptom score of the children in both groups were reduced compared with those before treatment, and the levels of all scores in the observation group were lower than those in the control group(P<0.05).The effective rate of treatment in the observation group was higher than that in the control group(P<0.05).After treatment, the levels of serum interleukin-4(IL-4),IL-6,and immunoglobulin E(IgE) of children in both groups were lower than those before treatment, and the levels of each index in the observation group were lower than those in the control group(P<0.05).After treatment, the scores of the Pediatric Allergic Rhinitis Quality of Life Questionnaire(RQLQ) in both groups was lower than that before treatment, and the level of RQLQ scores of the observation group was lower than that of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups of children compared to each other(P>0.05).The satisfaction of the families of the children in the observation group was higher than that of the control group(P<0.05).Conclusion:The combination of acupoint application with cetirizine hydrochloride drops and mometasone furoate nasal spray for the treatment of children with allergic rhinitis has a good clinical efficacy.It can regulate the immune function of children, improve various clinical symptoms, enhance the quality of life, and has good safety.更多还原