【摘要】 急性胰腺炎(AP)病因多样，病程凶险，其严重程度也不尽相同。肥胖是AP发病的危险因素，肥胖者AP发病风险及其严重程度均明显高于非肥胖者。肥胖患者相较于非肥胖患者的脂肪组织含量更多，脂肪组织尤其是内脏脂肪组织与AP严重程度的关系更为密切。本文就二者关系参阅相关文献，综合阐述内脏脂肪组织产生的脂肪因子及炎症介质致使全身炎症反应进而加重AP的作用机制，以期为临床深入研究二者关系提供参考。更多还原

【Abstract】 Acute pancreatitis(AP) has diverse causes and a dangerous course, with varying degrees of severity. Obesity is a risk factor for the development of AP, and the risk and severity of AP in obese individuals are significantly higher than those in non-obese individuals. Compared with non-obese patients, obese patients have a higher content of adipose tissue, especially visceral adipose tissue, which is more closely related to the severity of acute AP. This article consults relevant literature and comprehensively elaborates on the mechanism of fat factors and inflammatory mediators produced by visceral adipose tissue that cause systemic inflammatory response and further exacerbate AP, aiming to provide a reference for clinical in-depth study of the relationship between the two.更多还原