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维奈克拉耐药的潜在机制与应对策略
Possible mechanisms and clinical strategies of venetoclax resistance
【摘要】 维奈克拉为血液肿瘤患者带来了新的治疗选择,展现出优良的临床疗效。但随着药品应用开展,耐药逐步成为维奈克拉临床管理的焦点问题。为了维持持久有效的治疗结局,本文从多个角度综述血液系统肿瘤中维奈克拉的潜在耐药机制,并提出相应的解决对策,以期为未来有关研究提供参考依据。
【Abstract】 Venetoclax has brought new treatment options to patients with hematologic tumors and has demonstrated excellent clinical effect. However,with the development of drug application,drug resistance has gradually become the focus of clinical management. In order to achieve a lasting and effective treatment outcome and provide reference for future studies,this paper reviews the potential drug resistance mechanisms of venetoclax in hematological tumors from multiple perspectives,and proposes corresponding countermeasures.
【基金】 辽宁省教育厅2019年度科学研究经费项目(JC2019011)
- 【文献出处】 实用药物与临床 ,Practical Pharmacy and Clinical Remedies , 编辑部邮箱 ,2024年04期
- 【分类号】R979.1
- 【下载频次】31