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不孕不育人群生殖道沙眼衣原体感染影响因素分析

Chlamydia trachomatis infection and its associated factors among the infertility population

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【作者】 邓宝清叶云凤宁宁晏瑞琳温桂春黄李成邓勇峥袁青蔡于茂陈祥生

【Author】 DENG Baoqing;YE Yunfeng;NING Ning;YAN Ruilin;WEN Guichun;HUANG Licheng;DENG Yongzheng;YUAN Qing;CAI Yumao;CHEN Xiangsheng;Shenzhen Bao′an Center for Chronic Disease Control;Shenzhen Center for Chronic Disease Control;Institute of Dermatology and Hospital for Skin Diseases, Chinese Academy of Medical Sciences;National Center for Sexually Transmitted Disease Control, Chinese Center for Disease Control and Prevention;

【通讯作者】 蔡于茂;

【机构】 深圳市宝安区慢性病防治院深圳市慢性病防治中心中国医学科学院北京协和医学院皮肤病研究所中国疾病预防控制中心性病控制中心

【摘要】 目的 了解不孕不育门诊人群生殖道沙眼衣原体(CT)感染现状及影响因素,为制定该人群的CT防治策略提供依据。方法 2021年4—12月在深圳市宝安区4家开设有不孕不育门诊的医疗机构的常规就诊者中招募调查对象。在获得知情同意情况下,收集其社会人口学相关信息并采集尿液标本进行CT核酸检测。运用Logistic回归分析该人群CT感染的影响因素。结果 共招募954例不孕不育患者,CT阳性率为3.56%。Logistic回归分析结果表明,年龄<25岁(OR=3.91,95%CI:1.58~9.67)、文化程度为大专(OR=4.33,95%CI:1.23~15.24)、最近1年性伴数量≥2个(OR=4.25,95%CI:1.72~10.55)是该人群感染CT的危险因素。在调查对象中,74.42%不了解CT感染的相关症状,73.90%既往未检测过CT。结论 深圳市宝安区不孕不育人群CT感染率较高,性活跃年龄段、文化程度相对较低、有多个性伴是CT感染的危险因素,应在不孕不育专科门诊中针对以上人群开展CT筛查,同时开展健康宣传,提高人群生殖健康。

【Abstract】 Objective To reveal Chlamydia trachomatis(CT) infection and its associated factors among patients attending the infertility-related clinics in Bao′an District of Shenzhen in order to develop evidence-based strategies for interventions of CT in this population. Methods From April to December 2021, patients attending four infertility-related clinics in Bao′an District of Shenzhen were invited to participate in the survey using a recruitment approach. After an informed consent was obtained, each participant provided socio-demographic and behavioral information and urine samples for CT detection using a nucleic acid assay. Logistic regression was used to determine the factors associated with CT infection. Results Among a total of 954 participants, the prevalence of CT infection was 3.56 %. The logistic analysis showed that the risk factors of CT included individuals aged younger than 25 years(OR=3.91,95%CI:1.58~9.67),having junior college education(OR=4.33,95%CI:1.23~15.24)and having more than 2 sexual partners in the last year(OR=4.25,95%CI:1.72~10.55). The participants(74.42%) were unaware of symptoms of CT infection and 73.90% never had any prior screening for CT. Conclusions The CT infection rate is relatively high among the infertility population in Bao′an District, Shenzhen. The sexually active age, relatively low educational level, and multiple sexual partners are risk factors for CT infection. At infertility clinics, CT screening along with health education should be given to people at high risk of CT infection in order to improve the reproductive health.

【基金】 宝安区医疗卫生基础研究项目(2020JD112)
  • 【文献出处】 皮肤性病诊疗学杂志 ,Journal of Diagnosis and Therapy on Dermato-venereology , 编辑部邮箱 ,2024年02期
  • 【分类号】R711.6
  • 【下载频次】34
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