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中国多巴胺能PET联合葡萄糖代谢PET脑显像在帕金森病临床应用专家共识

Consensus on Clinical Application of “Dopaminergic-glucose” United PET Imaging in Parkinsonian Disorders in China

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【作者】 左传涛刘丰韬田梅管一晖张宏鲁佳荧李欣忆琚紫昭葛璟洁吴平张军罗巍豆晓锋于聪聪钟燕金晨涛周瑞侯海峰占宏伟卢洁王瑞民李彪尹雅芙李雪娜朱小华朱元凯兰晓莉姜磊何勇田蓉范岩孙夕林赵军富丽萍蒋韩马晓芬张丽霞丁正同王坚中国认知科学学会分子影像分会

【Author】 ZUO Chuan-tao;LIU Feng-tao;TIAN Mei;GUAN Yi-hui;ZHANG Hong;LU Jia-ying;LI Xin-yi;JU Zi-zhao;GE Jing-jie;WU Ping;ZHANG Jun;LUO Wei;DOU Xiao-feng;YU Cong-cong;ZHONG Yan;JIN Chen-tao;ZHOU Rui;HOU Hai-feng;ZHAN Hong-wei;LU Jie;WANG Rui-min;LI Biao;YIN Ya-fu;LI Xue-na;ZHU Xiao-hua;ZHU Yuan-kai;LAN Xiaoli;JIANG Lei;HE Yong;TIAN Rong;FAN Yan;SUN Xi-lin;ZHAO Jun;FU Li-ping;JIANG Han;MA Xiao-fen;ZHANG Li-xia;DING Zheng-tong;WANG Jian;Molecular Imaging Branch,Chinese Society for Cognitive Science;Department of Nuclear Medicine & PET Center,Huashan Hospital,Fudan University;Department of Neurology,Huashan Hospital,Fudan University;Department of Nuclear Medicine & PET Center,the Second Affiliated Hospital Zhejiang University School of Medicine;Department of Radiology,Huashan Hospital,Fudan University;Department of Neurology,the Second Affiliated Hospital Zhejiang University School of Medicine;Department of Radiology and Nuclear Medicine,Xuanwu Hospital,Capital Medical University;Department of Nuclear Medicine,the First Medical Centre,Chinese PLA General Hospital;Department of Nuclear Medicine,Ruijin Hospital,Shanghai Jiaotong University School of Medicine;Department of Nuclear Medicine,Xinhua Hospital,Shanghai Jiaotong University School of Medicine;Department of Nuclear Medicine,the First Hospital of China Medical University;Department of Nuclear Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology;Department of Nuclear Medicine,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology;PET Center,Department of Nuclear Medicine,Guangdong Provincial People’s Hospital;Department of Nuclear Medicine,Zhongnan Hospital,Wuhan University;Department of Nuclear Medicine,West China Hospital,Sichuan University;Department of Nuclear Medicine,Peking University First Hospital;Department of Nuclear Medicine,the Fourth Hospital of Harbin Medical University;Department of Nuclear Medicine,Shanghai East Hospital,Tongji University School of Medicine;Department of Nuclear Medicine,China-Japan Friendship Hospital;PET-CT Center,Fujian Medical University Union Hospital;Department of Nuclear Medicine,Guangdong Second Provincial General Hospital;Department of Nuclear Medicine,Zhejiang Provincial Hospital of Traditional Chinese Medicine;Molecular Imaging Branch,Chinese Society for Cognitive Science;

【通讯作者】 田梅;张宏;王坚;

【机构】 复旦大学附属华山医院核医学/PET中心复旦大学附属华山医院神经内科浙江大学医学院附属第二医院核医学科/PET中心复旦大学附属华山医院放射科浙江大学医学院附属第二医院神经内科首都医科大学宣武医院放射与核医学科中国人民解放军总医院第一医学中心核医学科上海交通大学医学院附属瑞金医院核医学科上海交通大学医学院附属新华医院核医学科中国医科大学附属第一医院核医学科华中科技大学同济医学院附属同济医院核医学科华中科技大学同济医学院附属协和医院核医学科广东省人民医院核医学科武汉大学中南医院核医学科四川大学华西医院核医学科北京大学第一医院核医学科哈尔滨医科大学附属第四医院核医学科同济大学附属东方医院核医学科中日友好医院核医学科福建医科大学附属协和医院PET/CT室广东省第二人民医院核医学科浙江省中医院核医学科中国认知科学学会分子影像分会

【摘要】 多巴胺能正电子发射断层扫描(PET)脑显像是目前诊断帕金森病的重要依据,但其对帕金森综合征的鉴别能力有限。葡萄糖代谢PET显像中不同的脑代谢模式为进一步鉴别诊断提供可能。文中在前期PET脑显像相关技术操作和临床应用专家共识的基础上,对开展多巴胺能联合葡萄糖代谢显像进行系统梳理,征求专家意见后形成本专家共识。旨在规范帕金森综合征患者的多巴胺能显像及葡萄糖代谢显像的技术操作,为医生提供报告解读建议,进一步指导多巴胺能与葡萄糖代谢PET脑显像联合应用在帕金森相关疾病中的临床实践流程。

【Abstract】 Dopaminergic positron emission computed tomography(PET) has been validated as an important supportive and exclusive criteria for the diagnosis of Parkinson’s disease. However, it is limited in the differential diagnosis of different kinds of parkinsonism. The different cerebral metabolic patterns in 18F-fluorodeoxyglucose PET imaging can facilitate the further differential diagnosis. Based on the previously published expert consensus for the operation procedure and clinical application of PET imaging, this expert consensus was formed after systematic combing of dopaminergic and glucose metabolism imaging. This consensus aimed to standardize the operation procedures of dopaminergic and glucose metabolism PET in parkinsonism, providing suggestions for the report interpretations, and further guiding the clinical practice using the “dopaminergic-glucose” united PET imaging in parkinsonism.

【基金】 国家自然科学基金(编号:82272039、82021002、82394430、82361148130、82030049);国家重点研发计划资助(编号:2022YFC2009902、2022YFC2009900)
  • 【文献出处】 中国临床神经科学 ,Chinese Journal of Clinical Neurosciences , 编辑部邮箱 ,2024年04期
  • 【分类号】R742.5
  • 【下载频次】26
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