【摘要】 目的 基于医患管家应用程序（肾关爱APP）管理模式下，对规律透析患者慢性肾脏病矿物质与骨代谢异常（chronic kidney disease-mineral bone disease,CKD-MBD）指标的调整及效果分析。方法 选取2021年8月至2022年3月期间于新疆维吾尔自治区人民医院及北京市垂杨柳医院行规律血液透析及腹膜透析的患者104例作为研究对象，用随机数字表法将其分为软件使用组和对照组，对照组为常规临床治疗CKD-MBD，软件使用组为APP管理模式下治疗CKD-MBD。对所有患者每3个月进行一次随访，累计随访12个月。记录患者血钙、血磷、血清甲状旁腺激素（intact parathyroid hormone,iPTH）的变化及患者满意度、复诊率等。结果 软件使用组第二次至第四次随访中iPTH达标率分别为69.2%、73.1%、67.3%高于对照组，相应的达标率（34.6%、34.6%和25.0%），差异有统计学意义（P<0.05），软件使用组患者满意度为73.47%显著高于对照组55.55%(P<0.05)。结论 采用APP管理模式的干预方式有利于改善规律透析患者的CKD-MBD相关指标达标率，改善患者依从性，提高患者满意度，具有临床推广意义。更多还原

【Abstract】 Objective To explore the adjustment and impact of chronic kidney disease-mineral and bone disorder(CKD-MBD) parameters in maintenance dialysis patients utilizing the Doctor-Patient Care App(Renal Care App). Methods From August 2021 to March 2022, 102 maintenance dialysis(HD) and peritoneal dialysis(PD) patients were randomized into two groups of App management or control(n=51 each). Control group received standard treatment for CKD-MBD while App management group was treated with CKD-MBD management model facilitated by Renal Care App. Follow-up assessments occurred every 3 months over a 12-month period. Changes in serum calcium(Ca), serum phosphorus(P) and serum parathyroid hormone(iPTH) levels were recorded along with patient satisfaction and revisit rates.Results From August 2021 to March 2022, 102 maintenance dialysis(HD) and peritoneal dialysis(PD)patients were randomized into two groups of App management or control(n=51 each). Control group received standard treatment for CKD-MBD while App management group was treated with CKD-MBD management model facilitated by Renal Care App. Follow-up assessments occurred every 3 months over a 12-month period. Changes in serum calcium(Ca), serum phosphorus(P) and serum parathyroid hormone(iPTH) levels were recorded along with patient satisfaction and revisit rates. Conclusions Interventions utilizing the App management model prove advantageous in elevating the rate of CKD-MBD-related parameters attaining the standards among regular dialysis patients. This approach not only improves patient compliance and satisfaction but also demonstrates clinical significance for broader applications.更多还原