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经颅磁刺激治疗强迫障碍的研究进展

Research progress of transcranial magnetic stimulation in the treatment of obsessive-compulsive disorder

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【作者】 杜若南罗阳黄伟皓张晓鸣谭云龙谭淑平杨甫德田宝朋王志仁

【Author】 DU Ruo-nan;LUO Yang;HUANG Wei-hao;ZHANG Xiao-ming;TAN Yun-long;TAN Shu-ping;YANG Fu-de;TIAN Bao-peng;WANG Zhi-ren;Peking University HuiLongGuan Clinical Medical School,Beijing Huilongguan Hospital;

【通讯作者】 王志仁;

【机构】 北京大学回龙观临床医学院北京回龙观医院

【摘要】 强迫障碍(obsessive-compulsive disorder, OCD)是一种严重的慢性失能性精神疾病,具有高共病率、高致残率、高误诊率的特点,这给家庭和社会造成了极大的负担。随着大量研究的展开,越来越多的研究结果表明重复经颅磁刺激(repetitive transcranial magnetic stimulation, rTMS)在OCD的治疗中起到了重要作用。本文系统阐述了近年来rTMS在OCD治疗中的相关研究,梳理了rTMS对OCD可能的起效机制,并对rTMS治疗OCD的常用位点、疗效及安全性进行综述,为将来rTMS在OCD的治疗中提供更多的可能性。

【Abstract】 Obsessive compulsive disorder(OCD) is a serious chronic disability mental disease, which has the characteristics of high comorbidity rate, high disability rate and high misdiagnosis rate.It has caused a great burden the family and society.With the development of a large number of studies, more and more research results show that repetitive transcranial magnetic stimulation(rTMS) plays an important role in the treatment of OCD.This review systematically expounds the relevant research of rTMS in the treatment of OCD in recent years, combs the possible effective mechanism of rTMS on OCD,and summarizes the common schemes, efficacy and safety of rTMS in the treatment of OCD,so as to provide more possibilities for rTMS in the treatment of OCD in the future.

【基金】 北京市科技计划项目(Z181100001518005,Z171100001017021,Z17110000107022);北京市医院管理局临床医学发展专项经费资助(XMLX202130)
  • 【文献出处】 临床精神医学杂志 ,Journal of Clinical Psychiatry , 编辑部邮箱 ,2024年06期
  • 【分类号】R749.7
  • 【下载频次】40
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