【摘要】 引起肝外胆管狭窄的病因很多，其中良性狭窄可以通过药物治疗及内镜干预获得较好的疗效。恶性狭窄如能早期诊断，并及时行手术治疗有望延长患者的生存期。然而，肝外胆管恶性狭窄的鉴别诊断迄今为止仍然较为困难。本文就血清学、影像学、内镜相关技术及人工智能技术在肝外胆管恶性狭窄鉴别诊断中的进展进行综述，以期为制订临床诊疗方案提供策略和参考。更多还原

【Abstract】 There are various etiologies for extrahepatic bile duct stenosis, and pharmacotherapy and endoscopic intervention can achieve a good clinical effect in benign stenosis. Early diagnosis and timely surgical treatment of malignant stenosis may prolong the survival time of patients. However, there are still difficulties in the differential diagnosis of malignant bile duct stenosis. This article reviews the application of serology, radiology, endoscopic techniques, and artificial intelligence in the differential diagnosis of malignant bile duct stenosis, so as to provide strategies and references for formulating clinical diagnosis and treatment regimens.更多还原