【摘要】 IgA血管炎(IgAV)是一种由IgA沉积在小血管引起的自身免疫性疾病，除了非血小板减少性紫癜表现，还有胃肠道、关节及肾脏受累。该病具有自限性，少数累及肾脏者，可在晚年发展为终末期肾脏疾病。文章对儿童IgAV临床特征及累及肾脏的相关机制进行综述，并探讨该病的治疗及预后。更多还原

【Abstract】 IgA vasculitis (IgAV) is an autoimmune disease caused by IgA deposition in small blood vessels.It is characterized by non-thrombocytopenic purpura,abdominal pain,joint swelling and pain,hematuria or proteinuria.The disease is self-limited,with only a minority progressing to end-stage renal disease in later life.This paper reviews the clinical features of IgAV in children and the mechanisms of renal involvement,and discusses the treatment and prognosis of the disease.更多还原