【摘要】 目的 比较艾司氯胺酮联合环泊酚与舒芬太尼联合环泊酚两种不同用药方式静脉全麻在老年短时宫腔镜手术中的运用情况。方法 选取我院择期行宫腔镜手术老年患者80例，按数字表法随机分为艾司氯胺酮+环泊酚组（EC组）和舒芬太尼+环泊酚组（SC组），每组40例。EC组患者予艾司氯胺酮0.125 mg/kg、环泊酚0.4 mg/kg、酮咯酸氨丁三醇30 mg静脉注射，SC组患者予舒芬太尼0.15μg/kg、环泊酚0.4 mg/kg、酮咯酸氨丁三醇30 mg静脉注射静脉全麻。记录两组患者全麻诱导前后MAP、HR、SpO₂及手术、苏醒时长。记录两组患者离手术室前不良反应发生情况。结果 与SC组相比，EC组患者麻醉诱导前后血流动力学更加稳定，围术期相关不良反应发生率降低（P<0.05）。结论 与舒芬太尼联合环泊酚相比，小剂量艾司氯胺酮联合环泊酚用于老年短时宫腔镜手术，患者血流动力学更稳定，围术期相关不良反应更少。更多还原

【Abstract】 Objective To compare the effects of intravenous general anesthesia with esketamine combined with cyclophenol and sufentanil combined with cyclophenol in elderly patients undergoing short-term hysteroscopic surgery. Methods Eighty elderly patients scheduled for hysteroscopic surgery were randomly divided into two groups: Group EC（n = 40） and group SC（n = 40）.The patients in EC group were injected intravenously with esketamine（0.125 mg/kg）, cyclophenol（0.4 mg/kg） and tromethamine ketorolac（30 mg）, patients in SC group were given sufentanil（0.15 μg/kg）, cyclophosphamide（0.4 mg/kg） and Ketorolac tromethamine（30 mg）. Map, HR, SpO₂, operation time and recovery time were recorded before and after induction of general anesthesia. The adverse reactions before leaving the operating room were recorded. Results Compared with group SC, patients in group EC had more stable hemodynamics and less perioperative adverse reactions（P<0.05）. Conclusion Compared with sufentanil combined with cyclophenol, low-dose esketamine combined with cyclophenol for short-term hysteroscopic surgery in the elderly has a more stable hemodynamics and less perioperative-related adverse effects.更多还原