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HUNK通过AGAP3/ARF6抑制小窝通路介导的货物摄取及内体到溶酶体运输(英文)

HUNK inhibits cargo uptake and lysosomal traffic in the caveolar pathway via the AGAP3/ARF6

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【作者】 蒋思远韩晓琦刘体慧何颖赵子栋刘桐凤程书文张吉航段利强刘雅娟程天佑刘勇叶琪浓高山

【Author】 Siyuan Jiang;Xiaoqi Han;Tihui Liu;Ying He;Zidong Zhao;Tongfeng Liu;Shuwen Cheng;Jihang Zhang;Liqiang Duan;Yajuan Liu;Tianyou Cheng;Yong Liu;Qinong Ye;Shan Gao;Zhongda Hospital, Medical School, Advanced Institute for Life and Health, Southeast University;Medical School of Guizhou University;Shanxi Academy of Advanced Research and Innovation;Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Southeast University;Nanjing University Medical School;Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Tai Kang Center for Life and Medical Sciences, Wuhan University;Department of Medical Molecular Biology, Beijing Institute of Biotechnology, Collaborative Innovation Center for Cancer Medicine;

【通讯作者】 高山;

【机构】 Zhongda Hospital, Medical School, Advanced Institute for Life and Health, Southeast UniversityMedical School of Guizhou UniversityShanxi Academy of Advanced Research and InnovationZhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Southeast UniversityNanjing University Medical SchoolHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Tai Kang Center for Life and Medical Sciences, Wuhan UniversityDepartment of Medical Molecular Biology, Beijing Institute of Biotechnology, Collaborative Innovation Center for Cancer Medicine

【摘要】 <正>Endocytosis is a crucial cellular process that takes up cargos by enclosing them in membrane-bound vesicles, and transports cargos to different parts of the cell, such as the lysosomes [1].Endocytosis is classified into several mechanistically and morphologically pathways, including clathrin-mediated endocytosis(CME)and caveolae-mediated endocytosis(Cav ME) [1,2].

【关键词】 内体AGAP3/ARF6HUNK小窝vesicles溶酶体classified英文通路运输
【基金】 supported by the National Natural Science Foundation of China (82025029 and 82150114);the National Key R&D Program of China (2022YFC3401000);the Fundamental Research Funds for the Central Universities
  • 【文献出处】 Science Bulletin ,科学通报(英文) , 编辑部邮箱 ,2024年02期
  • 【分类号】Q25
  • 【下载频次】10
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