【摘要】 目的 了解北京市昌平区居民中心型肥胖流行水平，并探讨中心型肥胖与心血管疾病危险因素及其聚集的关系。方法 基于2018—2019年昌平区开展的心血管病高危人群早期筛查与综合干预项目，对筛查点的35～75岁常住居民进行问卷调查、体格检查并采集生物样本，分析中心型肥胖检出率及不同程度中心型肥胖组高血压、糖尿病、血脂异常等心血管疾病危险因素水平及危险因素聚集情况。结果 纳入12 505名居民，中心型肥胖率为72.3%,标化率为70.0%。高血压、糖尿病和血脂异常等心血管疾病危险因素患病率、危险因素聚集率均随腰围增大而升高(P值均<0.05)。多因素logistic回归分析结果显示，轻度中心型肥胖组患高血压、糖尿病、血脂异常及危险因素聚集的风险分别是腰围正常组的1.95、1.70、1.72、1.85倍，重度中心型肥胖组患高血压、糖尿病、血脂异常及危险因素聚集的风险分别是腰围正常组的3.75、2.36、2.50、2.94倍。结论 北京市昌平区居民中心型肥胖率较高，中心型肥胖与心血管疾病危险因素及其聚集有关。加强中心型肥胖的预防和控制对心血管疾病的预防具有重要意义。更多还原

【Abstract】 Objective To investigate the prevalence of abdominal obesity among residents in Changping District, Beijing Municipality, and to examine the associations of abdominal obesity with risk factors and risk factor clusters of cardiovascular diseases. Methods Based on the early screening and comprehensive intervention programme among populations at a high risk of cardiovascular diseases in Changping District from 2018 to 2019,permanent residents at ages of 35 to 75 years from all screening sites received questionnaire surveys and physical examinations, and biological specimens were collected.The detection of abdominal obesity, prevalence of risk factors of cardiovascular diseases, including hypertension, diabetes and dyslipidemia, and clustering of risk factors were analyzed among abdominal obesity patients at various degrees of severity. Results A total of 12 505 residents were enrolled, and the prevalence and standardized prevalence of abdominal obesity were 72.3% and 70.0% among participants, respectively.The prevalence of cardiovascular diseases, including hypertension, diabetes and dyslipidemia, and clustering of risk factors increased with waist circumference(all P values < 0.05),and multivariate logistic regression analysis revealed that the risks of hypertension, diabetes and dyslipidemia and clustering of risk factors were 1.95,1.70,1.72 and 1.85 times higher among patients with mild abdominal obesity than among patients with normal waist circumference, and were 3.75,2.36,2.50 and 2.94 times higher among patients with severe abdominal obesity than among patients with normal waist circumference. Conclusions The prevalence of abdominal obesity is high among residents in Changping District, Beijing Municipality, and correlates with risk factors and risk factor clusters of cardiovascular diseases.Intensified prevention and control of abdominal obesity is of great significance for prevention of cardiovascular diseases.更多还原