【摘要】 目的 分析福建省戊型病毒性肝炎(简称戊肝)的流行趋势和时空聚集性。方法 通过中国疾病预防控制信息系统收集2014―2023年福建省戊肝报告发病数据，运用Joinpoint 5.1.0.0模型描述报告发病率的变化趋势，使用SaTScan V9.5软件进行时空扫描分析。结果 2014―2023年福建省共报告戊肝病例8 108例，年均报告发病率为2.05/10万，2014―2020年呈下降趋势(APC=-7.41%, 95%CI:-22.09%～2.25%,P=0.009),2020―2023年呈上升趋势(APC=15.95%, 95%CI:0.94%～42.43%,P=0.034)。戊肝主要流行季节在冬春季，男性戊肝报告发病率高于女性(χ~2=583.42,P<0.001),报告发病率随年龄的增长总体呈上升趋势(趋势χ~2=4 607.00,P<0.001)。时空扫描分析发现7类戊肝空间聚集区域。结论 2014―2023年福建省戊肝报告发病率呈先下降后上升趋势，中老年男性为主要发病人群，发病分布存在时空聚集性，需加强高危人群和热点地区的戊肝监测和防控。更多还原

【Abstract】 Objective To analyze the epidemic trend and spatiotemporal clustering of hepatitis E in Fujian Province. Methods The reported incidence data of hepatitis E in Fujian Province from 2014 to 2023 were collected through the China information system for disease control and prevention. The change trend of the reported incidence rate was described using the Joinpoint 5.1.0.0 model. Spatiotemporal scanning analysis was performed using SaTScan V9.5 software. Results A total of 8108 cases of hepatitis E were reported in Fujian Province during 2014-2023,for an average annual reported incidence of 2.05 per 100 000. there was a downward trend(APC=-7.41%, 95% CI:-22.09%-2.25%, P=0.009), while from 2020 to 2023, there was an upward trend(APC=15.95%, 95% CI: 0.94%-42.43%, P=0.034). The main epidemic season was winter and spring. The reported incidence rate of hepatitis E in men was higher than that in women(χ~2=583.42, P<0.001), and the reported incidence rate showed an over all upward trend with the increase of age(χ~2=4 607.00, P<0.001). The spatiotemporal scan analysis has revealed seven types of spatial clustering areas for hepatitis E. Conclusions From 2014 to 2023,the reported incidence rate of hepatitis E in Fujian Province showed a downward trend and then an upward trend middle aged and elderly men were the main affected population, and the incidence was spatiotemporal clustering. It was necessary to strengthen the monitoring of hepatitis E in high-risk groups and hot spots.更多还原