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发热伴血小板减少综合征感染防控专家共识
Expert consensus on prevention and control of severe fever with thrombocytopenia syndrome
【摘要】 发热伴血小板减少综合征(severe fever with thrombocytopenia syndrome, SFTS)是主要通过蜱虫叮咬使患者感染大别班达病毒(Dabie bandavirus, DBV)的新发传染病。2009年首次在我国中部地区发热伴白细胞及血小板减少患者的血清中分离到该病原体，现在亚洲多个国家流行，重症患者死亡率高。近10年来，国内外关于DBV因人际传播而引发SFTS聚集性的疫情事件时有发生。尤其重症患者容易引起人际传播事件发生，在其抢救和治疗过程中因防护不规范易发生院内感染而导致医护人员感染病毒。因此，迫切需要制定防控DBV人际传播的合理措施，控制疫情蔓延，对临床SFTS重症患者的管理有重要的指导意义和临床价值。为了更好地规范DBV人际传播防控策略，研究邀请了该领域的知名专家进行深入讨论，在SFTS的流行概况、患者的血液和体液接触传播、病毒气溶胶传播、患者的污染物及遗体处理等关键防控措施方面达成了共识。
【Abstract】 Severe fever with thrombocytopenia syndrome(SFTS) is an emerging infectious disease caused by Dabie bandavirus(DBV) transmitted through tick bites. It was initially identified in 2009 among febrile patients with leukopenia and thrombocytopenia in central China. SFTS has been recently reported in other Asia countries, resulting in high mortality among severely ill patients. In the recent 10 years, there have been some reports about human-to-human transmission of DBV, particularly among severely ill patients. However, there are currently no established prevention and control measures for medical staff during the clinical treatment for severely ill SFTS patients against human-to-human transmission. Improper precaution measure can cause nosocomial infection of DBV among medical staff during the clinical process of rescue and treatment. Therefore, it is crucial to develop preventive and control measures against DBV′s human-to-human transmission, which would significantly contribute to the management of severely ill SFTS patients. To better regulate the precaution measures strategies against DBV human-to-human transmission, we have invited renowned experts in this field for extensive discussions, and reached a consensus on prevention and control measures concerning SFTS epidemiological features, contact transmission through patient′s blood and bloody secretions, aerosol transmission, as well as patient′s contaminants handling and corpse disposal.
【Key words】 Severe fever with thrombocytopenia syndrome； Dabie bandavirus； Human-to-human communication； Precaution measures；
- 【文献出处】 中华疾病控制杂志 ,Chinese Journal of Disease Control and Prevention , 编辑部邮箱 ,2024年06期
- 【分类号】R512.8;R183
- 【下载频次】261