【摘要】 目的 观察牙周基础治疗联合米诺环素治疗慢性单纯性牙龈炎的疗效。方法 选择2018年4月至2023年6月我院慢性单纯性牙龈炎患者100例，以信封随机法分为对照组和研究组，各50例，对照组实施牙周基础治疗，研究组加以米诺环素治疗，观察两组牙周指标的变化、不良反应发生情况以及治疗效果。结果治疗后，两组各牙周指标均有改善，研究组探诊深度(PD)小于对照组，菌斑指数(PLI)、龈沟出血指数(SBI)明显低于对照组，总治疗率明显高于对照组，差异有统计学意义(P<0.05)；两组不良反应情况相近，差异无统计学意义(P>0.05)。结论 牙周基础治疗联合米诺环素治疗慢性单纯性牙龈炎患者疗效显著，可改善患者牙周指标，且具有较高的安全性。更多还原

【Abstract】 Objective To observe the effect of periodontal non-surgical treatment combined with minocycline in the treatment of chronic simple gingivitis.Methods One hundred patients with chronic simple gingivitis admitted to the hospital from April 2018 to June 2023 were selected and divided into control group and study group by envelope randomisation method, 50 cases each, respectively receiving periodontal non-surgical treatment and periodontal non-surgical treatment combined with minocycline. Changes in periodontal indices, incidences of adverse reactions and therapeutic effects in the two groups were observed. Results After treatment, periodontal indices in both groups were improved. The probing depth(PD),plaque index(PLI) and sulcus bleeding index(SBI) were smaller/lower in study group than the control group, and the overall treatment rate was higher than that of the control group, with a statistically significant difference(P<0.05). There is no statistically significant difference in incidences of adverse reactions of the two groups(P>0.05). Conclusion The combined treatment of periodontal non-surgical treatment and minocycline is significantly effective for patients with chronic simple gingivitis. It can improve periodontal indices, with high safety.更多还原