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云南巴豆中倍半萜类化合物的研究
Study on Sesquiterpenoids from Croton yunnanensis
【摘要】 云南巴豆(Croton yunnanensis)枝叶风干粉碎后用甲醇提取,使用硅胶柱层析、MCI柱层析、Sephadex LH-20凝胶柱层析及HPLC等分离技术对其化学成分进行分离纯化,得到5个倍半萜类化合物,分别是(-)-ent-6α-methoxyeudesm-4(15)-en-1β-ol (1), oplodiol (2),(7R~*)-opposit-4(15)-ene-1β,7-diol (3), aphanamol I (4)和orientalol C (5)。化合物11-4为首次从该种植物中分离得到。
【Abstract】 The branches and leaves of Croton yunnanensis were dried and extracted with methanol. The chemical components were separated and purified by silica gel column chromatography, MCI column chromatography, Sephadex LH-20 gel column chromatography and HPLC. These compounds were identified as(-)-ent-6α-methoxyeudesm-4(15)-en-1β-ol(1),oplodiol(2),(7R~*)-opposit-4(15)-ene-1β,7-diol(3), aphanamol I(4) and orientalol C(5). Compounds 1-4 were isolated from this plant for the first time.
【Key words】 Croton yunnanensis; sesquiterpenoids; chemical constituents; structural identification;
- 【文献出处】 海南师范大学学报(自然科学版) ,Journal of Hainan Normal University(Natural Science) , 编辑部邮箱 ,2024年01期
- 【分类号】R284.1
- 【下载频次】19