【摘要】 目的：探讨对糖尿病高危青少年人群实施基于国家标准化代谢性疾病管理中心（MMC）模式干预的应用效果，为降低青少年人群糖尿病发病率提供依据。方法：选取2021年春季学期佳木斯市3所高中的学生进行随机血糖筛查，筛选其中葡萄糖耐量减低（IGT）和空腹血糖异常的61例学生进行住院治疗，采用计算机单盲随机分组法将其分为对照组30例和研究组31例。对照组患者采用常规护理干预，研究组患者实施基于MMC模式的护理干预。比较两组患者糖脂代谢指标、自我护理行为[中文修订版Morisliy服药依从性量表（MMAS-8）评分]、疾病转归情况。结果：干预后，研究组患者糖脂代谢指标均低于对照组，差异有统计学意义（t=7.565、3.945、3.664、7.925,P<0.05）。干预后，研究组患者MMAS-8中各维度评分均高于对照组，差异有统计学意义（t=5.442、24.843、11.672、40.221、5.336、19.732,P<0.05）。研究组患者未发生糖尿病酮症酸中毒和糖尿病，疾病不良转归总发生率明显低于对照组，差异有统计学意义（χ~2=4.016,P<0.05）。结论：对糖尿病高危青少年人群实施MMC模式干预，能够及早发现糖尿病，控制血糖，改善患者糖脂代谢指标，提高自我护理行为能力，降低糖尿病发病率，促进疾病转归。更多还原

【Abstract】 Objective:To explore the applied effects of implementing interventions based on the national standardized Metabolic Management Center (MMC) model in a population of adolescents at high risk for diabetes,and to provide a basis for reducing the incidence of diabetes in the adolescent population.Methods:Students from three high schools in Jiamusi in the spring semester of2021 were selected for random glycemic screening,and 61 of them with impaired glucose tolerance (IGT) and abnormal fasting glucose were screened for hospitalization,and were divided into a control group of 30 and a study group of 31 using a computerized single-blind randomization grouping method.The control group used conventional nursing interventions,and the study group implemented nursing interventions based on the MMC model.Glycolipid metabolism indexes,self-care behaviors[Chinese Revised Morisliy Medication Adherence Scale (MMAS-8) score],and disease regression were compared between the two groups.Results:After the intervention,the glycemic and lipid metabolism indexes of the study group were lower than those of the control group and the differences were statistically significant (t=7.565,3.945,3.664,7.925,P<0.05).After the intervention,the scores of all dimensions in the MMAS-8 were higher in the study group than in the control group,and the difference was statistically significant(t=5.442,24.843,11.672,40.221,5.336,19.732,P<0.05).No diabetic ketoacidosis or diabetes mellitus occurred in the study group,and the total incidence of adverse disease regression was significantly lower than that in the control group,with a statistically significant difference (χ~2=4.016,P<0.05).Conclusion:Implementation of the MMC model of intervention for adolescents at high risk for diabetes can lead to early detection of diabetes,glycemic control,improvement of patients’glycemic and lipid metabolism indexes,enhancement of self-care behaviors,reduction of diabetes morbidity,and promotion of disease regression.更多还原