节点文献
2C-B的亚慢性毒性研究
Study on subchronic toxicity of 2C-B
【摘要】 研究4-溴-2,5-二甲氧基苯乙胺(4-bromo-2,5-dimethoxyphenethylamine, 2C-B)的亚慢性毒性.通过对大鼠进行长期连续染毒,以体重变化、脏器系数、病理学检查及肝肾生化酶水平的影响探讨2C-B对机体造成损伤的情况.综合各指标结果分析长期服用2C-B会对心脏、肝脏、肺脏、肾脏、大脑产生损害,上述器官可能是2C-B毒性的靶器官.
【Abstract】 To study the subchronic toxicity of 4-bromo-2,5-dimethoxyphenethylamine(2C-B). The damage caused by 2C-B to the body was investigated by weight change, viscera coefficient, pathological examination and the effects on liver and kidney biochemical enzyme levels in rats through long-term continuous exposure. According to the results of various indexes, long-term administration of 2C-B will cause damage to the heart, liver, lung, kidney and brain, and these organs may be the target organs of 2C-B toxicity.
【关键词】 2C-B;
亚慢性毒性;
脏器系数;
病理学检查;
肝肾生化酶水平;
【Key words】 4-bromo-2,5-dimethoxyphenethylamine; subchronic toxicity; viscera coefficient; pathological examination; liver and kidney biochemical enzyme levels;
【Key words】 4-bromo-2,5-dimethoxyphenethylamine; subchronic toxicity; viscera coefficient; pathological examination; liver and kidney biochemical enzyme levels;
【基金】 黑龙江省重点研发计划项目(GA21C021)
- 【文献出处】 哈尔滨商业大学学报(自然科学版) ,Journal of Harbin University of Commerce(Natural Sciences Edition) , 编辑部邮箱 ,2024年03期
- 【分类号】R114
- 【下载频次】12