【摘要】 目的 探讨泰州市大气NO₂对儿童门诊就诊量的影响。方法 收集泰州市2023年1月1日—12月31日气象资料（包括日平均温度、日平均相对湿度、日平均气压）、环保资料(包括每日PM₁₀、PM_2.5、SO₂、NO₂、CO、O_{3-8 h}平均质量浓度)以及同期某综合性医院儿科门诊就诊数据。通过广义相加模型的时间序列分析方法，分析泰州市大气NO₂浓度与同期儿科门诊就诊人次的关系。结果 Spearman相关分析显示，大气污染物NO₂与其他大气污染物SO₂、CO、O_{3-8 h}、PM₁₀和PM_2.5均存在正相关（P<0.05）。单污染物模型中，当NO₂日均质量浓度每升高10μg/m³时，其对当日呼吸系统疾病门诊量和日门诊总量均产生了明显影响，分别增加0.48%（95%CI:0.18%～0.77%）、0.16%（95%CI:0.04%～0.27%）。多污染物模型中，纳入其他5种污染物(SO₂、CO、PM₁₀、PM_2.5、O_{3-8 h})后，NO₂质量浓度的变化对儿童呼吸系统疾病门诊量和儿童日门诊总量的影响仍有统计学效应（P<0.05）。结论 泰州市NO₂质量浓度与本次调查的儿童门诊就诊风险增加有相关性，且存在滞后效应。更多还原

【Abstract】 Objective To understand the effect of atmospheric NO₂ on visits of the pediatric department in Taizhou City.Methods From January 1,2023 to December 31,2023,the daily meteorological information （daily mean temperature,humidity and atmospheric pressure）,and air pollutants(PM_2.5,PM₁₀,SO₂,NO₂ and O_{3-8 h})and the daily data of pediatric outpatient visits in a general hospital during the same period.The relationship between NO₂ concentration and daily pediatric outpatient visits in Taizhou was analyzed by generalized additive model （GAM）.Results Spearman correlation analysis showed that air pollutant NO₂ was positively correlated with other air pollutants SO₂,CO,O_{3-8 h},PM₁₀ and PM_2.5（P<0.05）.Significant associations were showed between NO₂ and children daily outpatient volume and respiratory department visiting （lag0）,and ERs were 0.16%（95%CI:0.04%-0.27%） and 0.48%（95%CI:0.18%-0.77%） associated with an increase of 10μg/m³NO₂.After controlling other pollutants(SO₂,CO,PM₁₀,PM_2.5,O_{3-8 h}) simultaneously,significant association were still found between NO₂ and children daily outpatient amount and respiratory department visits （P<0.05）.Conclusion Atmospheric NO₂ pollution level has a significant impact on visits of the pediatric department in Taizhou City,with a certain lagged effect.更多还原