【摘要】 目的 探讨封闭式负压引流术对创伤性胫骨骨髓炎术后患者创面愈合及骨愈合指标中的应用价值。方法 选取108例创伤性胫骨骨髓炎术后患者作为研究对象，根据创面诊疗方式将患者分为两组（对照组和观察组）。其中对照组（n=54）例采取常规清创治疗，观察组（n=54）例行封闭式负压引流术，对比两组患者骨髓炎炎症指标、创面愈合指标、骨愈合指标、生活自理能力、感染发生率。结果 手术后，观察组患者白细胞计数（WBC）水平、红细胞沉降率（ESR）水平及超敏C反应蛋白（CRP）水平均低于对照组患者（P<0.05）；观察组患者创面愈合时间、患者住院时间、骨折愈合时间及外固定超出时间均低于对照组患者（P<0.05）；手术后，观察组患者躯体功能评分及认知功能评分均高于对照组患者（P<0.05）；两组患者感染发生率对比差异无统计学意义（P>0.05）。结论 创伤性胫骨骨髓炎术后患者在接受封闭式负压引流术治疗后可加快创面愈合速度，提高患者的预后生活自理能力，降低骨髓炎炎症指标。更多还原

【Abstract】 Objective To investigate the application value of closed negative pressure drainage in wound healing and bone healing indexes of patients after traumatic tibial osteomyelitis.Methods 108 patients with postoperative traumatic tibial osteomyelitis were selected as the study objects,and the patients were divided into two groups(control group and observation group)according to the wound diagnosis and treatment methods.The control group(n=54)was treated with routine debridement,and the observation group(n=54)was treated with closed negative pressure drainage.The inflammation indexes of osteomyelitis,wound healing indexes,bone healing indexes,self-care ability,and incidence of infection were compared between the two groups.Results After operation,the levels of white blood cell count(WBC),erythrocyte dust reduction rate(ESR)and hypersensitive C-reactive protein(CRP)in observation group were lower than those in control group(P<0.05).The wound healing time,hospital stay,fracture healing time and external fixation time in observation group were lower than those in control group(P<0.05).After operation,the scores of physical function and cognitive function in observation group were higher than those in control group(P<0.05).There was no significant difference in the incidence of infection between two groups(P>0.05).Conclusion Closed negative pressure drainage can accelerate wound healing,improve patients’ self-care ability and reduce the inflammatory index of traumatic tibial osteomyelitis.更多还原