【摘要】 目的 探讨运用精细化管理策略，在结直肠癌患者手术部位感染（SSI）防控的应用价值及实践效果。方法 由医院感染管理科牵头运用精细化管理策略，在广西医科大学附属肿瘤医院开展基于精细化管理的结直肠癌患者SSI防控实践，2020年7月至2023年6月在该院实施医院感染精细化管理后，通过比较该院结直肠癌患者的SSI发生情况，来评价精细化管理的实施效果。结果 实施医院感染精细化管理后，2020年7月至2023年6月，接受手术治疗的结直肠癌患者的SSI发生率为1.68%，且呈逐年下降趋势，差异有统计学意义（P <0.05）。按结肠癌根治术、直肠癌根治术及其他肠道手术分类，其中结肠癌根治术的SSI发生率逐年下降，差异有统计学意义（P <0.05）。发生吻合口瘘为SSI最主要的感染原因（71.74%）。SSI检出病原菌中，大肠埃希菌检出率最高（62.16%）。结论 运用精细化管理方法，将临床学科与感控学科交叉融合，多项举措并施为患者创造更优的围手术期条件，可进一步降低结直肠癌患者SSI发生率，提高医疗质量、保障医疗安全，助力公立医院高质量发展。更多还原

【Abstract】 Objective To explore the application value and practical effect of using refined management strategies in the prevention and control of surgical site infections(SSI) in colorectal cancer patients. Methods Infection Prevention and Control Department took the lead in implementing the practice of prevention and control of SSI for colorectal cancer patients in the Guangxi Medical University Cancer Hospital. From July 2020 to June 2023, after the implementation of hospital infection refined management in the hospital, the implementation effect of refined management was evaluated by comparing the occurrence of SSI in colorectal cancer patients in this hospital. Results From July 2020 to June 2023, the incidence of SSI in patients with colorectal cancer who underwent surgical treatment was 1.68%, and it showed a decreasing trend year by year, with statistically significant difference(P < 0.05). According to the classification of colon cancer radical surgery, rectal cancer radical surgery, and other intestinal surgeries, the incidence of SSI in colon cancer radical surgery decreased year by year, and the difference was statistically significant(P < 0.05). The occurrence of anastomotic leakage was the main cause of SSI infection(71.74%). Among the pathogenic bacteria detected by SSI, the detection rate of Escherichia coli was the highest(62.16%). Conclusion By using refined management methods, integrating clinical and sensory control disciplines, and implementing multiple measures to create better perioperative conditions for patients, the incidence of SSI in colorectal cancer patients can be further reduced, medical quality can be improved, medical safety can be guaranteed, and high-quality development of public hospitals can be assisted.更多还原