节点文献

柚皮素的药理学特性及在呼吸系统疾病中的研究进展

Pharmacological properties of naringin and research progress of its therapeutic efficacies in respiratory diseases

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 高雯雯赵洁吴福玲马立吉

【Author】 GAO Wenwen;ZHAO Jie;WU Fuling;MA Liji;Department of Pediatrics, Binzhou Medical University Hospital;Department of Pediatrics, Zibo Central Hospital,Shandong;

【通讯作者】 吴福玲;马立吉;

【机构】 滨州医学院附属医院儿科山东省淄博市中心医院儿科

【摘要】 柚皮素是一种属于黄酮类化合物的天然多酚类植物化学物质,被证实具备多种生物和药理活性,包括抗炎、抗氧化、抗过敏、抗病毒、抗肿瘤、免疫调节、抗糖尿病、抗动脉粥样硬化和神经保护等,其具有重要的药用价值,已成为多种疾病的潜在治疗药物。近年越来越多的研究发现,柚皮素对哮喘、肺炎、肺纤维化、肺损伤和肺癌等呼吸系统疾病均存在保护作用。因此,本文将基于柚皮素的药理学特性就其在呼吸系统疾病中作用机制的最新研究进展做一综述,以期为柚皮素的临床应用提供理论依据。

【Abstract】 Naringin is a natural polyphenol phytochemical substance, belonging to a subclass of flavonoids. It has been proved to allow for an extensive variety of biological and pharmacological actions, including therapeutic effect on inflammation, oxidative stress, allergic symptoms, viral infections, cancers, immunological diseases,diabetes, atherosclerosis, and nerve diseases, thus has important medicinal value and has become a promising drug for treating many diseases. In recent years, more and more studies have found that naringin has therapeutic effects on such respiratory diseases as asthma, pneumonia, pulmonary fibrosis, lung injury, and lung cancer.Therefore, literature review on the latest research progress on the pharmacological properties of naringin and its mechanisms of action in treating respiratory diseases was presented in this paper, hoping to provide a theoretical basis for its clinical application.

【基金】 山东省自然科学基金项目(ZR2014HL001)
  • 【文献出处】 中国医药科学 ,China Medicine and Pharmacy , 编辑部邮箱 ,2024年07期
  • 【分类号】R285
  • 【下载频次】88
节点文献中: 

本文链接的文献网络图示:

本文的引文网络