【摘要】 口腔颌面部肿瘤是口腔颌面外科的常见疾病，以虚拟手术设计、手术导航为代表的数字化外科技术目前已成为口腔颌面部肿瘤外科诊治的主要辅助手段。然而，现有的数字化技术在三维可视化成像、术中手眼配合等方面仍存在提升空间。目前，以混合现实技术为代表的三维可视化技术已经在医学领域迅速发展和应用，通过将三维虚拟图像叠加到真实的手术环境中，可辅助实现医学影像实时立体呈现，已逐步应用于口腔颌面部肿瘤的诊治中。术前可基于影像数据构建肿瘤及其周边重要结构三维模型，在混合现实环境中，进行个性化术前评估和手术方案设计；术中将混合现实技术与手术导航技术相结合，可以在术区真实环境中实时显示三维虚拟模型，克服单纯使用导航技术的手眼协调问题，进一步提高口腔颌面部肿瘤手术的精确性和安全性。混合现实技术与远程互联网医疗技术相结合，还可以提供高质量的教学平台，推动地区口腔颌面外科诊疗水平的发展。混合现实技术的局限性主要在于术区影像遮挡、单纯使用时精度不足、配准时间长等。笔者结合国内外文献报道以及本课题组的临床实践，对混合现实技术在口腔颌面部肿瘤诊疗中的应用进行归纳与总结。更多还原

【Abstract】 Oral and maxillofacial tumors are common oral and maxillofacial surgery-related diseases. Digital surgical technology, represented by virtual surgical design and surgical navigation, is the main auxiliary means of the surgical diagnosis and treatment of oral and maxillofacial tumors. However, the existing digital technology still has some problems and room for improvement in terms of 3D visualization imaging and intraoperative hand-eye coordination. At present,the application of 3D visualization technology represented by mixed-reality technology has been rapidly developing in the medical field. It assists in realizing the real-time stereoscopic presentation of medical images by superimposing 3D virtual images onto the real surgical environment. Mixed-reality technology has been gradually applied to the diagnosis and treatment of oral and maxillofacial tumors. Preoperatively, mixed-reality technology can be used to construct a 3D model of the tumor and its surrounding vital structures based on imaging data, at which point the medical team can personalize the preoperative assessment and design the surgical plan in the mixed-reality environment. Intraoperatively, the combination of mixed-reality technology and surgical navigation technology can be used to display the 3D virtual model in real time in the actual environment of the operation area, overcoming the hand-eye coordination problem associated with using navigation technology alone and further improving the accuracy and safety of oral and maxillofacial tumor surgery. The combination of mixed-reality technology and internet medical technology can provide a high-quality teaching platform to promote the development of regional oral and maxillofacial surgery practices. The limitations of mixed-reality technology include image occlusion, lack of accuracy when used alone, and long alignment times. In this review, the application of mixed-reality technology to the diagnosis and treatment of oral and maxillofacial tumors will be summarized and assessed by combining information from domestic and international literature reports with the practical clinical experience of the author group.更多还原