【摘要】 目的 了解电子厂工人高尿酸血症的患病情况及危险因素，为电子厂工人健康保护提供依据。方法 选择武汉市某电子厂1 415名职工为研究对象，进行体检及各项生化指标测定，同时进行问卷和体格检查。结果 武汉市某电子厂工人高尿酸血症检出率为32.43%,男性为36.33%、女性为14.11%,差异有统计学意义(χ~2=46.077,P<0.001)。大学或大专学历者高尿酸血症检出率最高(33.77%),其次为研究生及以上(31.50%)。与生活行为习惯良好者相比，有饮酒习惯的调查对象高尿酸血症检出率较高(49.38%),差异有统计学意义(P=0.001)。有向心性肥胖，谷丙转氨酶升高者的调查对象者高尿酸血症检出率分别为48.23%、61.29%,明显高于无上述疾病的调查对象(分别为26.91%、27.21%),差异均有统计学意义(P<0.001)。肥胖者高尿酸血症检出率最高(66.95%),其次为超重者(43.75%),差异有统计学意义(P<0.001)。多因素分析显示，饮酒(AOR=1.836,95%CI:1.139～2.961,P=0.013)、体质指数≥24kg/m~2(AOR=2.175,95%CI:1.686～2.806,P<0.001)是电子厂工人HUA发病的危险因素；ALT升高与高尿酸关联有统计学意义(AOR=2.964,95%CI:2.146～4.095,P<0.001);而女性是武汉市某电子厂工人HUA的保护因素(AOR=0.441,95%CI:0.297～0.653,P<0.001)。结论 武汉市某电子厂工人高尿酸血症检出率较高，男性高尿酸血症检出率高于女性，饮酒、超重、肥胖、均会增加高尿酸血症发生的风险，谷丙转氨酶升高与高尿酸血症存在关联性。维持理想体重指数，建立良好的生活方式对预防高尿酸血症起重要作用。更多还原

【Abstract】 Objective To understand the prevalence and risk factors of hyperuricemia in electronics factory workers in Wuhan, and to provide evidence for the health protection of electronics factory workers. Methods A total of 1 415 employees in an electronics factory in Wuhan were selected as the research subjects, and the physical examination and determination of various biochemical indicators, as well as questionnaire survey were carried out. Results The detection rate of hyperuricemia among workers in the electronics factory in Wuhan was 32.43%,with 36.33% for men and 14.11% for women, and the difference was statistically significant(χ~2=46.077,P<0.001).The detection rate of hyperuricemia was the highest(33.77%) among those with university or college education, followed by graduate students and above(31.50%).Compared with subjects with good lifestyle habits, people with drinking habits had higher hyperuricemia detection rate(49.38%),and the difference was statistically significant(P=0.001).The detection rates of hyperuricemia in those with central obesity and elevated alanine aminotransferase were 48.23% and 61.29%,respectively, which were significantly higher than those in the subjects without the above diseases(26.91% and 27.21%,respectively),and the differences were statistically significant(P<0.001).Obese people had the highest detection rate of hyperuricemia(66.95%),followed by overweight people(43.75%),and the difference was statistically significant(P<0.001).Multivariate logistic analysis showed that alcohol drinking(OR=1.836,95% CI=1.139-2.961,P=0.013) and body mass index ≥24 kg/m~2(OR=2.175,95% CI=1.686-2.806,P<0.001) were risk factors for hyperuricemia in electronic factory workers.Elevated alanine aminotransferase(ALT) was significantly correlated with hyperuricemia(OR=2.964,95% CI=2.146-4.095,P<0.001).Female gender was a protective factor for hyperuricemia in workers in the electronics factory(OR=0.441,95% CI=0.297-0.653,P<0.001). Conclusion The detection rate of hyperuricemia among workers in an electronics factory in Wuhan is high, and the detection rate of hyperuricemia in men is higher than that in women.Alcohol consumption, overweight and obesity will increase the risk of hyperuricemia.Elevated ALT is associated with hyperuricemia.Maintaining an ideal body mass index and establishing a good lifestyle play an important role in preventing hyperuricemia.更多还原