【摘要】 RNA解螺旋酶DDX5(DEAD-box RNA helicase 5)又称RNA解螺旋酶p68蛋白，是一种广泛存在于真核生物中的重要蛋白质，在调节RNA的生物学过程中发挥着多种重要功能，包括转录、剪接、翻译和RNA稳定性的调节等。随着生命科学的发展和技术的进步，越来越多的研究表明，DDX5在肿瘤中的作用十分重要，不仅可以促进肿瘤的发生和发展，还可以作为潜在的治疗靶点和治疗监测指标。因此，针对DDX5在肿瘤发生发展中的作用机制进行深入研究，对于深入理解肿瘤的发生机制，以及制定有效的抗肿瘤治疗策略具有重要的意义，论文对DDX5的结构特点、生物学功能、在肿瘤中的作用机制及其研究进展进行了综述。更多还原

【Abstract】 RNA-lytic helicase DDX5(DEAD-box RNA helicase 5),also known as RNA-lytic helicase p68 protein, is an important protein widely present in eukaryotes, which plays a variety of important functions in regulating the biological process of RNA,including transcription, splicing, translation and regulation of RNA stability.With the development of life sciences and the advancement of technology, more and more studies have shown that the role of DDX5 in tumors is very important, which can not only promote the occurrence and development of tumors, but also serve as a potential therapeutic target and treatment monitoring index.Therefore, an in-depth study of the mechanism of DDX5 in tumorigenesis and development is of great significance for the in-depth understanding of tumor pathogenesis and the formulation of effective anti-tumor treatment strategies.In order to summarize the role of DDX5 in tumorigenesis and development and provide more options for tumor treatment, the structural characteristics, biological functions, mechanism of action in tumors, and its research progress are reviewed.更多还原