【摘要】 甲状腺癌发病与环境因素密切相关，环境变化导致的基因突变和腺体组织分子生物学改变是诱发甲状腺癌的重要因素之一。尽管甲状腺癌的相关分子机制仍未完全阐明，但随着分子生物学技术的发展，越来越多的甲状腺癌特定遗传改变和分子标志物被挖掘出来。本文就甲状腺癌的病因、特异性分子标志物、诊断及靶向治疗研究进展进行综述，为甲状腺癌的临床诊疗提供理论支持。更多还原

【Abstract】 Thyroid carcinoma is closely related to environmental factors. Gene mutations and molecular biological changes of gland tissue caused by environmental changes are important factors inducing thyroid carcinoma. Although the molecular mechanism of thyroid carcinoma has not been fully elucidated, increasingly specific genetic changes and molecular markers for thyroid carcinoma have been discovered with the development of molecular biology techniques. This article reviews the recent progresses on the etiology, specific molecular markers, diagnosis and targeted therapies of thyroid carcinoma, so as to provide theoretical support for the clinical diagnosis and treatment of thyroid carcinoma.更多还原