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腺样体和(或)扁桃体消融切除术患儿术后发生3度及以上出血的影响因素分析

Analysis of influencing factors of postoperative hemorrhage with degree 3 or above in children with adenoidectomy and/or tonsillectomy

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【作者】 陈莹; 程毅菁; 刘军廷; 占小俊; 潘守东; 谷庆隆;

【Author】 Chen Ying;Cheng Yijing;Liu Junting;Zhan Xiaojun;Pan Shoudong;Gu Qinglong;Department of Anesthesiology, Children’s Hospital, Capital Institute of Pediatrics;

【通讯作者】 谷庆隆;

【机构】 首都儿科研究所附属儿童医院麻醉科; 首都儿科研究所附属儿童医院儿童健康大数据研究中心; 首都儿科研究所附属儿童医院耳鼻咽喉头颈外科;

【摘要】 目的 探讨腺样体和扁桃体消融切除术患儿术后发生3度以上出血的影响因素。方法 选取2018年1月至2023年12月首都儿科研究所附属儿童医院行腺样体和(或)扁桃体消融切除术患儿,根据术后是否发生3度及以上出血分为未出血组和出血组。采用倾向性得分匹配(prospensity score matching, PSM)1∶4的比例进行匹配,采用多因素logistic回归方程分析腺样体和(或)扁桃体消融切除患儿术后发生3度及以上出血的影响因素。结果 共纳入患儿7 805例,其中男5 087例、女2 718例,年龄1~18岁,平均(5.6±2.1)岁,发生3度及以上术后出血26例(3.3‰),原发性出血22例(84.6%),其中14例发生于术后6 h内;继发性出血4例(15.4%),均发生于术后5.5~9 d。PSM共成功匹配26对。多因素logistic回归分析结果显示,BMI越大(OR=18.266,95%CI:1.502~22.099,P=0.023)、手术部位为扁桃体伴或不伴腺样体切除(OR=42.540,95%CI:35.585~49.938,P <0.001)的患儿,术后发生3度及以上出血的风险越高。结论 腺样体和(或)扁桃体消融切除术患儿术后3度及以上出血的发生率较低,主要发生于术后24 h内。BMI和手术部位是术后发生3度及以上出血的影响因素。

【Abstract】 Objective To explore the influencing factors of postoperative hemorrhage with degree 3 or above in children with adenoidectomy and/or tonsillectomy. Methods Children who underwent adenoidectomy and/or tonsillectomy in Children’s Hospital, Capital Institute of Pediatrics from January 2018 to December 2023 were selected, and were divided into non-bleeding group and bleeding group according to whether postoperative hemorrhage with degree 3 or above occurred or not. The ratio of propensity score matching(PSM) was 1: 4, and influencing factors of postoperative hemorrhage with degree 3 or above in children with adenoidectomy and/or tonsillectomy were analyzed by multivariate logistic regression equation. Results A total of 7 805 children were included, there were 5 087 males and 2 718 females,aged from 1 to 18 years, with an average age of(5.6 ± 2.1)years. There were 26 cases of postoperative hemorrhage with degree 3 or above, and the incidence rate was 3.3‰. There were 22 cases(84.6%) of primary bleeding, of which 14 cases occurred within 6 h after operation and four cases(15.4%) of secondary bleeding, all of which occurred at 5.5-9 d after operation. A total of 26 pairs were successfully matched by PSM. Multivariate logistic regression analysis results showed that children with higher BMI(OR = 18.266,95%CI: 1.502-22.099,P = 0.023)and the surgical site involves tonsillectomy with or without adenoidectomy(OR = 42.540,95%CI: 35.585-49.938,P < 0.001)had higher risks of postoperative hemorrhage with degree 3 or above. Conclusions The incidence of postoperative hemorrhage with degree 3 or above in children with adenoidectomy and/or tonsillectomy is low, and mainly occurred within 24 h after the operation. BMI and surgical site are the influencing factors of postoperative hemorrhage with degree 3 or above.

  • 【文献出处】 北京医学 ,Beijing Medical Journal , 编辑部邮箱 ,2024年09期
  • 【分类号】R766.9
  • 【下载频次】20
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