【摘要】 采用溶剂热法合成了分散性良好的Fe₃O₄粒子，然后将油酸修饰到Fe₃O₄粒子表面，再通过疏水作用进行十六烷基三甲基氯化铵（CTAC）包覆，得到Fe₃O₄@CTAC粒子。采用扫描电子显微镜（SEM）、X射线光电子能谱（XPS）、X射线衍射（XRD）、Zeta电位和振动样品磁强计（VSM）对Fe₃O₄@CTAC粒子进行了表征，结果表明：Fe₃O₄粒子表面包覆CTAC后粒径无明显变化，并且仍保持良好的单分散性；Fe₃O₄@CTAC粒子具有超顺磁性和良好的磁响应性能；Fe₃O₄@CTAC粒子的Zeta电位较高，分散体系具有较好的稳定性。对Fe₃O₄@CTAC粒子进行了抗菌性能及磁分离去除菌体测试，结果显示：当Fe₃O₄@CTAC粒子的含量为50 mg/mL时，与大肠杆菌（E.coli）（10⁵ cfu/mL）作用10 min,抗菌率可达100%;Fe₃O₄@CTAC粒子对E.coli、金黄色葡萄球菌（S.aureus）及枯草芽孢杆菌（B.subtilis）均具有良好的抗菌效果；通过磁场分离可以将Fe₃O₄@CTAC粒子及吸附的菌体去除。以上结果表明Fe₃O₄@CTAC粒子是一种快速、高效、可以实现无菌体残留的抗菌剂，具有潜在的应用价值。更多还原

【Abstract】 Fe₃O₄ particles with good dispersibility were synthesized by a solvothermal method. The surface of the Fe₃O₄ particles was first modified with oleic acid and cetyltrimethylammonium chloride（CTAC） was then coated via hydrophobic interactions to obtain Fe₃O₄@CTAC particles. The Fe₃O₄@CTAC particles were characterized by scanning electron microscopy（SEM）, X-ray photoelectron spectroscopy（XPS）, X-ray diffraction（XRD）, Zeta potential measurements and vibrating sample magnetometry（VSM）. The results show that the particle size of Fe₃O₄ has no obvious change after coating with CTAC, and the Fe₃O₄@CTAC particles retain good monodispersity. The Fe₃O₄@CTAC particles have superparamagnetism and good magnetic response properties. The Zeta potential of Fe₃O₄@CTAC particles is high, and the dispersion has good stability. The antibacterial properties and magnetic separation of Fe₃O₄@CTAC particles were tested. The results showed that when 50 mg/mL Fe₃O₄@CTAC particles were treated with E. coli（10⁵ cfu/mL） for 10 min, the antibacterial rate could reach 100%. Fe₃O₄@CTAC particles also have good antibacterial effects on S. aureus and B. subtilis. The Fe₃O₄@CTAC particles and adsorbed bacteria can be separated using a magnetic field. The above results indicate that Fe₃O₄@CTAC is a fast, efficient antibacterial agent that can generate aseptic residues and thus has potential application value.更多还原