【摘要】 目的 探讨磁共振-弥散加权成像（MR-DWI）对喉癌T分期的诊断价值及预后的预测价值。方法 158例喉癌手术患者均于术前、放疗后6个月接受MRI检查。以病理检查结果为金标准，比较常规MRI和MRDWI检查对喉癌的检出情况及其诊断喉癌T分期的结果与病理检查结果的一致性，以及不同预后喉癌患者MRDWI检查的表现弥散系数（ADC）值。结果 MR-DWI检查对喉癌的检出率明显高于常规MRI检查，差异有统计学意义（P﹤0.01）。MR-DWI检查诊断喉癌T分期的结果与病理检查结果的一致性Kappa值为0.869，高于常规MRI检查的0.703。放疗后6个月，未复发患者的ADC值明显高于复发患者，差异有统计学意义（P﹤0.01）。结论 MR-DWI检查对喉癌的检出率较高，其诊断喉癌术前T分期的结果与病理检查结果的一致性也较高，并且能预测喉癌患者的预后。更多还原

【Abstract】 Objective To investigate the diagnostic value of magnetic resonance-diffusion weighted imaging(MRDWI) for T-staging of laryngeal cancer and its prognostic predictive value. Method A total of 158 patients with laryngeal cancer underwent MRI examination before surgery and 6 months after radiotherapy. Pathological examination results were used as the gold standard, the detection of laryngeal cancer by conventional MRI and MR-DWI examination, the consistency between the results of T-stage diagnosis of laryngeal cancer by conventional MRI and MR-DWI examination and the results of pathological examination, and the apparent diffusion coefficient(ADC) values of MR-DWI examination in patients with different prognosis of laryngeal cancer were compared. Result The detection rate of laryngeal cancer by MR-DWI examination was significantly higher than that by conventional MRI examination, and the difference was statistically significant(P<0.01). The Kappa value for consistency between the results of MR-DWI examination and and the results of pathological examination in the diagnosis of T stage of laryngeal cancer was 0.869, which was higher than0.703 of conventional MRI examination. At 6 months after radiotherapy, ADC value of patients with no recurrence was significantly higher than that of patients with recurrence, and the difference was statistically significant(P<0.01). CCoonncclluu-sion The detection rate of laryngeal cancer by MR-DWI examination is high. The consistency between the results of MR-DWI examination and and the results of pathological examination in the diagnosis of T stage of laryngeal cancer is also high, which can predict the prognosis of laryngeal cancer patients.更多还原