【摘要】 抑郁症是临床常见的精神疾患，已成为严重的公共健康问题。肠道菌群失调与抑郁症发病密切相关。肠道菌群主要通过与“肠-脑轴”交互，影响抑郁症的发生和发展。目前西医主要应用药物治疗抑郁症，但不良反应较大。中医药治疗抑郁症安全性高、不良反应少，具有独特优势。作者从单味中药及其有效成分、中药复方以及针灸3个方面，对近5年来中医药治疗抑郁症的文献进行综述，梳理了中医药通过干预肠道菌群发挥抗抑郁作用的机制及临床效果，为中医药防治抑郁症提供理论和科学依据。更多还原

【Abstract】 Depression is a common clinical mental disorder and has become a serious public health problem. Studies have shown that the imbalance of intestinal flora is closely related to the onset of depression. Intestinal flora mainly affects the occurrence and development of depression through the interaction with “gut-brain axis”. At present, Western medicine mainly uses drugs to treat depression,but the side effects are severe. Traditional Chinese medicine(TCM) is a safe way to treat depression and has fewer untoward reactions with a special preponderance. From three aspects of single Chinese medicine and its effective components, TCM compound and acupuncture, the author summed up the TCM literature in the treatment of depression in the past five years and arranged the mechanism and treatment effect of TCM intervention on intestinal flora, offering a theoretical and scientific basis for the prevention and treatment of depression with TCM.更多还原