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胶质淋巴转运MRI研究进展

Research progresses of MRI in glymphatic transport

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【作者】 陈心怡卢艳丽桂千王琳辉

【Author】 CHEN Xinyi;LU Yanli;GUI Qian;WANG Linhui;Department of Physiology and Neurobiology,School of Biology & Basic Medical Sciences,Suzhou Medical College of Soochow University;Department of Radiology,Suzhou Hospital Affiliated to Nanjing Medical University[Suzhou Municipal Hospital];Department of Neurology,Suzhou Hospital Affiliated to Nanjing Medical University[Suzhou Municipal Hospital];

【通讯作者】 王琳辉;

【机构】 苏州大学苏州医学院基础医学与生物科学学院生理学与神经生物学系南京医科大学附属苏州医院(苏州市立医院)影像科南京医科大学附属苏州医院(苏州市立医院)神经内科

【摘要】 胶质淋巴系统(GS)是由星形胶质细胞终足上的水孔蛋白4(AQP4)介导的脑脊液和脑组织液交换流动系统,主要作用在于运输营养和清除脑内废物等。MRI能直接、迅速、无创显示脑脊液流动,可用于研究GS。本文就MRI研究GS进展进行综述。

【Abstract】 The glymphatic system(GS) has been described as one that facilitates the exchange between cerebrospinal fluid and interstitial fluid depending on the aquaporin-4(AQP4) water channels expressed in astrocytic end-feet,which mainly playing role in transporting nutrients and removing waste in the brain.MRI can directly,rapidly and noninvasively show the flow of cerebrospinal fluid,being used to study GS.The research progresses of MRI for GS were reviewed in this article.

【基金】 国家自然科学基金面上项目(31871167)
  • 【文献出处】 中国医学影像技术 ,Chinese Journal of Medical Imaging Technology , 编辑部邮箱 ,2023年08期
  • 【分类号】R445.2;R741
  • 【下载频次】53
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