【摘要】 目的 了解浙江省宁波市2018—2021年出生儿童肠道病毒71型（EV71）疫苗接种情况，为制定EV71疫苗接种策略提供依据。方法 通过浙江省预防接种管理系统收集宁波市2018—2021年出生儿童的人口学资料和EV71疫苗接种资料，分析EV71疫苗接种率、全程接种率和及时接种率。结果 宁波市2018—2021年共出生416 176人，其中男童216 977人，占52.14%；女童199 199人，占47.86%。EV71疫苗接种率为61.50%，全程接种率为58.70%，及时接种率为32.53%。常住儿童EV71疫苗接种率、全程接种率和及时接种率分别为71.43%、70.04%和40.24%，高于流动儿童的54.05%、50.18%和26.73%（均P<0.05）。城区儿童EV71疫苗接种率、全程接种率和及时接种率分别为67.72%、65.06%和40.37%，高于郊县儿童的54.11%、51.14%和23.21%（均P<0.05）。2018—2021年出生儿童EV71疫苗接种率分别为54.98%、61.24%、65.10%和66.72%，全程接种率分别为52.16%、58.72%、62.44%和63.39%，及时接种率分别为22.47%、25.86%、39.14%和48.03%，均呈上升趋势（均P<0.05）。结论 宁波市2018—2021年出生儿童EV71疫苗接种率、全程接种率和及时接种率均呈上升趋势，但及时接种率仍较低，需针对郊县、流动儿童加强EV71疫苗接种宣传。更多还原

【Abstract】 Objective To investigate the coverage of enterovirus 71(EV71) vaccine among children born between 2018and 2021 in Ningbo City, Zhejiang Province, so as to provide insights into formulating EV71 vaccination strategy.Methods Data pertaining to demography and EV71 vaccination among children born between 2018 and 2021 in Ningbo City were obtained from the Zhejiang Immunization Information Management System, and the coverage of vaccination,full-dose vaccination and timely vaccination of EV71 vaccine were analyzed.ResultsTotally 416 176 children were born between 2018 and 2021, including 216 977 boys(52.14%) and 199 199 girls(47.86%). The coverage rates of vaccination, full-dose vaccination and timely vaccination was 61.50%, 58.70% and 32.53%, respectively. The coverage rates of vaccination, full-dose vaccination and timely vaccination among local children(71.43%, 70.04% and 40.24%) were higher than those among migrant children(54.05%, 50.18% and 26.73%; P<0.05). The coverage rates of vaccination,full-dose vaccination and timely vaccination among urban children(67.72%, 65.06% and 40.37%) were higher than those among rural children(54.11%, 51.14% and 23.21%; P<0.05). The coverage rates of vaccination were 54.98%,61.24%, 65.10% and 66.72%, the coverage rates of full-dose vaccination were 52.16%, 58.72%, 62.44% and 63.39%,and the coverage rates of timely vaccination were 22.47%, 25.86%, 39.14% and 48.03% by the born year from 2018 to2021, all showing increasing trends year by year(P<0.05).Conclusions The coverage of vaccination, full-dose vaccination and timely vaccination of EV71 vaccine appears a tendency towards a rise among the 2018-2021 birth cohorts in Ningbo City, while the coverage of timely vaccination need to be improved. Health education for EV71 vaccination should be enhanced for rural and migrant children.更多还原