【摘要】 目的 了解2011—2022年浙江省宁波市胃癌发病和死亡趋势，为完善胃癌防制策略提供依据。方法 通过宁波市慢性病发病监测系统和死因监测系统收集2011—2022年宁波市胃癌发病和死亡资料，计算粗发病率和粗死亡率；采用2010年中国第六次人口普查数据计算中国人口标化率（中标率），采用Segi’s 1960世界标准人口构成计算世界人口标化率（世标率）；采用年度变化百分比（APC）和平均年度变化百分比（AAPC）分析胃癌发病和死亡趋势。结果 2011—2022年宁波市胃癌粗发病率为45.69/10万，无明显变化趋势（AAPC=-0.02%,P>0.05）；中标发病率和世标发病率分别为28.61/10万和21.87/10万，均呈下降趋势（AAPC=-3.19%、-3.05%，均P<0.05）。粗死亡率、中标死亡率和世标死亡率分别为28.56/10万、17.07/10万和12.57/10万，均呈下降趋势（AAPC=-3.00%、-6.26%、-6.34%，均P<0.05）。城市和农村居民胃癌中标发病率、世标发病率、中标死亡率和世标死亡率均呈下降趋势（城市：AAPC=-2.72%、-2.53%、-5.91%、-5.96%，均P<0.05；农村：AAPC=-3.61%和-3.53%、-6.79%、-6.89%，均P<0.05）；城市居民上述指标均高于农村居民。男性和女性胃癌中标发病率、世标发病率、中标死亡率和世标死亡率均呈下降趋势（男性：AAPC=-3.18%、-3.00%、-5.82%、-5.91%，均P<0.05；女性：AAPC=-2.98%、-2.90%、-7.12%、-7.12%，均P<0.05）；男性上述指标均高于女性。宁波市居民胃癌粗发病率和粗死亡率均随年龄增长呈上升趋势（均P<0.05）。结论 2011—2022年宁波市居民胃癌发病率和死亡率均呈下降趋势，但发病和死亡水平仍较高，应重点关注男性和城市居民，加强40岁及以上人群胃癌筛查。更多还原

【Abstract】 Objective To investigate the trends in incidence and mortality of gastric cancer in Ningbo City, Zhejiang Province from 2011 to 2022, so as to provide insights into improving gastric cancer control strategy.Methods The incidence and mortality of gastric cancer in Ningbo City from 2011 to 2022 were collected through Ningbo Municipal Chronic Disease and Cause of Death Monitoring System. The incidence and mortality of gastric cancer were calculated,and standardized by the data from the Sixth Chinese National Population Census in 2020(Chinese-standardized rate)and the world standard population first introduced by Segi in 1960(world-standardized rate). The trends in incidence and mortality of gastric cancer were evaluated using annual percent change(APC) and average annual percent change(AAPC).Results The crude incidence of gastric cancer was 45.69/10~5in Ningbo City from 2011 to 2022, with no significant changing patterns seen during the study period(AAPC=-0.02%, P>0.05), and the Chinese-and world-standardized incidence of gastric cancer was 28.61/10~5 and 21.87/10~5, which both appeared a tendency towards a decline(AAPC=-3.19% and-3.05%, both P<0.05). The crude, Chinese-standardized and world-standardized mortality rates of gastric cancer were 28.56/10~5, 17.07/10~5and 12.57/10~5, respectively, all showing a tendency towards a decline(AAPC=-3.00%,-6.26% and-6.34%, all P<0.05). The Chinese-and world-standardized incidence and mortality of gastric cancer all appeared a tendency towards a decline in urban(AAPC=-2.72%,-2.53%,-5.91% and-5.96%, all P<0.05)and rural areas(AAPC=-3.61%,-3.53%,-6.79% and-6.89%, all P<0.05), and the Chinese-and world-standardized incidence and mortality of gastric cancer were significantly higher among urban residents than among rural residents.The Chinese-and world-standardized incidence and mortality of gastric cancer all appeared a tendency towards a decline among men(AAPC=-3.18%,-3.00%,-5.82% and-5.91%, all P<0.05) and women(AAPC=-2.98%,-2.90%,-7.12% and-7.12%, all P<0.05), and the Chinese-and world-standardized incidence and mortality of gastric cancer was significantly higher among men than among women. In addition, the crude incidence and mortality of gastric cancer both appeared a tendency towards a rise with age among residents in Ningbo City(both P<0.05).Conclusions The incidence and mortality of gastric cancer both appeared a tendency towards a decline in Ningbo City from 2011 to 2022;however, the incidence and mortality remained high. Males and urban residents should be given a high priority for gastric cancer control, and gastric cancer screening should be strengthened among individuals at ages of 40 years and older.更多还原