【摘要】 目的 了解浙江省宁波市艾滋病病毒感染者和艾滋病患者（HIV/AIDS）新型毒品使用情况，为HIV/AIDS病例新型毒品监测和干预提供依据。方法 通过中国疾病预防控制信息系统艾滋病综合防治信息系统随机抽取宁波市HIV/AIDS病例为研究对象，采用问卷调查收集一般人口学信息、新型毒品使用和确证后性行为等；采集研究对象头发，采用液相色谱-质谱联用法检测冰毒、K粉和摇头丸等新型毒品；采用多因素logistic回归模型分析新型毒品使用的影响因素。结果 调查HIV/AIDS病例254例，其中男性214例，占84.25%。年龄<25岁31例，占12.20%;25～<31岁66例，占25.98%;31～75岁157例，占61.81%。自我报告既往使用过新型毒品30例，占11.81%；其中使用冰毒27例，占90.00%。头发检测新型毒品阳性48例，阳性率为18.90%；主要为冰毒，44例占91.67%。多因素logistic回归分析结果显示，年龄（25～<31岁，OR=6.926,95%CI:1.412～33.969）、职业（学生/教师/干部职员/离退休人员，OR=6.971,95%CI:2.123～22.889；家政、家务及待业人员，OR=3.356,95%CI:1.289～8.739；商业服务/公共场所服务人员，OR=2.447,95%CI:1.033～4.448）和近6个月感染过梅毒（OR=3.491,95%CI:1.664～7.326）是HIV/AIDS病例使用新型毒品的影响因素。结论 宁波市HIV/AIDS病例存在使用新型毒品现象，年龄、职业、梅毒感染与HIV/AIDS病例新型毒品使用有关。更多还原

【Abstract】 Objective To investigate the use of new types of drugs among HIV/AIDS patients in Ningbo City, Zhejiang Province, so as to provide insights into surveillance and interventions for use of new types of drugs among HIV/AIDS patients. Methods The HIV/AIDS patients in Ningbo City were randomly sampled from the HIV/AIDS Prevention and Control Information System of Chinese Disease Prevention and Control Information System. Patients’ demographics, use of new types of drugs and sexual behaviors were collected using questionnaire surveys. Patients’ hair samples were collected, and new types of drugs were determined in hair using liquid chromatography-mass spectrometry(LC-MS). In addition, factors affecting the use of new types of drugs were identified using a multivariable logistic regression model.Results A total of 254 HIV/AIDS patients were enrolled, including 214 men(84.25%), 31 cases aged under 25 years(12.20%), 66 cases aged 25 to 30 years(25.98%), and 157 cases aged 31 to 75 years(61.81%). There were 30 cases reported previous use of new drugs(11.81%), including 27 cases reported previous use of methamphetamine(90.00%).There were 48 cases tested positive of new types of drugs, with a positive rate of 18.90%, including 44 cases tested positive for methamphetamine(91.67%). Multivariable logistic regression analysis identified age(25 to 30 years, OR=6.926, 95%CI: 1.412-33.969), occupation(students/teachers/cadres/employees/retirees, OR=6.971, 95%CI: 2.123-22.889;housekeeping and housework servants/unemployed, OR=3.356, 95%CI: 1.289-8.739; business/public place servants, OR=2.447, 95%CI: 1.033-4.448) and syphilis infection during recent six months(OR=3.491, 95%CI: 1.664-7.326) as factors affecting the use of new types drugs among HIV/AIDS patients. Conclusions The use of new types of drugs exists in HIV/AIDS patients in Ningbo City. Age, occupation and syphilis infection were associated with the use of new types of drugs among HIV/AIDS patients.更多还原