【摘要】 目的 探究急性脑梗死患者血清胱抑素C及凝血功能的临床检验价值。方法 选取60例急性脑梗死患者设为实验组,同期60例健康体检者设为对照组。比较两组受检者的凝血酶原时间、活化部分凝血活酶时间、纤维蛋白原、血清胱抑素C水平；比较实验组不同分型患者的凝血酶原时间、活化部分凝血活酶时间、纤维蛋白原、血清胱抑素C水平。结果 实验组的凝血酶原时间(10.55±1.17)s、活化部分凝血活酶时间(28.67±2.46)s短于对照组的(12.59±2.38)、(38.55±3.01)s,纤维蛋白原(3.43±1.01)g/L、血清胱抑素C(1.68±0.52)mg/L高于对照组的(2.06±0.44)g/L、(1.15±0.11)mg/L,差异具有统计学意义(P<0.05)。实验组患者分为进展型29例、完全型31例。完全型患者的凝血酶原时间(11.48±2.01)s、活化部分凝血活酶时间(31.29±2.98)s长于进展型患者的(9.17±1.15)、(26.44±2.15)s,纤维蛋白原(2.77±0.54)g/L、血清胱抑素C(1.39±0.22)mg/L低于进展型患者的(3.98±1.03)g/L、(2.08±0.45)mg/L,差异具有统计学意义(P<0.05)。结论 血清胱抑素C、凝血功能检验在急性脑梗死患者的临床检验中价值显著,可有效鉴别疾病,在急性脑梗死患者具体分型中参考价值高,可大力推行、应用。更多还原

【Abstract】 Objective To investigate the clinical test value of serum cystatin C and coagulation function in patients with acute cerebral infarction. Methods 60 patients with acute cerebral infarction were selected as the experimental group, and 60 healthy subjects were selected as the control group. The prothrombin time, activated partial thromboplastin time, fibrinogen and serum cystatin C levels were compared between the two groups; the prothrombin time, activated partial thromboplastin time, fibrinogen and serum cystatin C levels were compared among patients of different subtypes in the experimental group. Results The prothrombin time of(10.55±1.17) s and activated partial thrombin time of(28.67±2.46) s in the experimental group were shorter than those of(12.59±2.38) and(38.55±3.01) s in the control group; the fibrinogen of(3.43±1.01) g/L and cystatin C of(1.68±0.52) mg/L in the experimental group were higher than those of(2.06±0.44) g/L and(1.15±0.11) mg/L in the control group; the differences were statistically significant(P<0.05). There were 29 cases of progressive cerebral infarction and 31 cases of complete cerebral infarction. The prothrombin time of(11.48±2.01) s and activated partial thrombin time of(31.29±2.98) s of patients with complete cerebral infarction were longer than those of(9.17±1.15) and(26.44±2.15) s of patients with progressive cerebral infarction; the fibrinogen of(2.77±0.54) g/L and cystatin C of(1.39±0.22) mg/L in patients with complete cerebral infarction were lower than those of(3.98±1.03) g/L and(2.08±0.45) mg/L in patients with progressive cerebral infarction;the differences were statistically significant(P<0.05). Conclusion Serum cystatin C and coagulation function test have significant value in acute cerebral infarction patients, and can effectively identify the disease. It is of high reference value in the specific classification of patients with acute cerebral infarction patients, and can be vigorously promoted and applied.更多还原