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人巨细胞病毒感染母婴研究进展

Research progress of human cytomegalovirus infection in mothers and newborns

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【作者】 庞晓燕王鑫王晓华赵建平

【Author】 PANG Xiaoyan;WANG Xin;WANG Xiaohua;ZHAO Jianping;Inner Mongolian Maternity and Child Health Care Hospital;Clinical Medical College, Inner Mongolia Medical University;

【通讯作者】 王晓华;赵建平;

【机构】 内蒙古自治区妇幼保健院内蒙古医科大学内蒙古临床医学院内蒙古自治区人民医院检验科

【摘要】 人巨细胞病毒(human cytomegalovirus,HCMV)是世界广泛传播的传染病病原体,孕妇妊娠期间感染此病毒后会垂直传染给胎儿,导致胎儿发育异常和智力下降,并可引起新生儿神经发育和听力异常等疾病。新生儿感染后可无症状,因此容易被忽视而产生严重后遗症,影响新生儿的发育和健康。目前国际国内诊治意见尚不统一,对于母婴感染的诊断和新生儿的筛查方面仍存在很多问题。本文结合近年来的专家共识和研究进展,从人巨细胞病毒的病原学特点、流行病学、传播途径、实验室检查、诊断方法和治疗等方面进行综述,以期了解母婴巨细胞病毒感染的临床特点和诊治进展,为临床提供帮助。

【Abstract】 Human cytomegalovirus(HCMV) is a worldwide infectious disease pathogen, which can be vertically transmitted to the fetuses after mother’s infection during pregnancy, resulting in abnormal fetal development and mental decline, and neurological development and hearing abnormalities in the newborns. Neonatal infections can be asymptomatic, so they are easy to be ignored and have serious sequelae, affecting the development and health of the newborns. At present, the international and domestic diagnosis and treatment opinions are not unified, and there are still many problems in the diagnosis of mother-to-child infection and newborn screening. Based on the expert consensus and research progress in recent years, this paper reviews the etiological characteristics, epidemiology, transmission routes, laboratory tests, diagnostic methods and treatment of HCMV in order to understand the clinical characteristics, diagnosis and treatment progress of maternal and infant cytomegalovirus infections, and provide clinical assistance.

  • 【文献出处】 中国病毒病杂志 ,Chinese Journal of Viral Diseases , 编辑部邮箱 ,2023年06期
  • 【分类号】R714.251
  • 【下载频次】34
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