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人用狂犬病疫苗及其应用研究进展

Research progress in human rabies vaccine applications

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【作者】 随海田郭星张倩杨中楠苏锦锋张杨殷文武舒祥

【Author】 SUI Hai-tian;GUO Xing;ZHANG Qian;YANG Zhong-nan;SU Jin-feng;ZHANG Yang;YIN Wen-wu;SHU Xiang;China National Biotec Group;Division of Infectious Diseases of Chinese Center for Disease Control and Prevention;

【通讯作者】 殷文武;舒祥;

【机构】 中国生物技术股份有限公司中国疾病预防控制中心传染病管理处

【摘要】 狂犬病是由狂犬病毒引起的人兽共患疾病,尚无有效治疗方法,其预防措施主要为暴露前或暴露后接种人用狂犬病疫苗。随着科技的进步,人用狂犬病疫苗的生产工艺不断发展创新,疫苗质量不断提高,为人类抵抗狂犬病提供了更安全、有效的防控手段。然而,狂犬病免疫预防目前亟待解决疫苗接种依从性差、接种率低等难题。我国须积极探索有效应对策略,加速更新现有免疫程序,切实提高狂犬病疫苗接种率,尽早实现2030年消除狂犬病的目标。

【Abstract】 Rabies is a zoonosis caused by rabies virus for which no effective treatment is available. The main preventive measure is vaccination with human rabies vaccine before or after rabies exposure. With progress in science and technology, the production process of human rabies vaccine has continually advanced, thereby increasing vaccine quality, and providing a safer, more effective means of rabies prevention and control through increasing human resistance to rabies. New human rabies vaccines have made breakthroughs in basic research and clinical research. However, the problems of poor vaccine compliance and low vaccination rates must urgently be addressed. China must actively explore effective coping strategies, accelerate the updating of existing immunization procedures, effectively increase the rabies vaccination rate, and achieve the goal of eliminating rabies by 2030 as soon as possible.

【关键词】 狂犬病人用狂犬病疫苗安全性免疫原性
【Key words】 rabieshuman rabies vaccinesafetyimmunogenicity
  • 【文献出处】 中国人兽共患病学报 ,Chinese Journal of Zoonoses , 编辑部邮箱 ,2023年12期
  • 【分类号】R186
  • 【下载频次】79
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