【摘要】 目的 分析1990—2019年浙江省居民伤害疾病负担及其变化趋势，为伤害防制策略的制定提供依据。方法 利用2019年全球疾病负担（GBD 2019）中国分省研究结果，选取死亡率、过早死亡损失寿命年（YLL）率、伤残损失寿命年（YLD）率和伤残调整寿命年（DALY）率等指标。采用GBD 2019世界标准人口进行标化。采用SAS 9.4软件和Excel 2016软件对1990—2019年浙江省居民的伤害疾病负担进行描述。应用Joinpoint 4.9.1.0软件计算各指标的平均年度变化百分比（AAPC）。结果 2019年浙江省居民伤害标化死亡率为44.79/10万，标化DALY率为2 243.74/10万。1990—2019年浙江省居民伤害标化死亡率、标化YLL率和标化DALY率均呈下降趋势（AAPC分别为-2.12%、-3.13%和-2.37%,P<0.01）。浙江省伤害标化死亡率与全国同期水平接近，标化YLL率、标化DALY率均低于全国水平，标化YLD率高于全国水平。2019年浙江省道路交通伤的标化DALY率和标化YLL率均居首位。1990—2019年浙江省男性居民伤害标化死亡率、标化YLL率、标化YLD率、标化DALY率均高于女性，但是女性YLD在DALY中的构成比高于男性。不同年龄组伤害疾病负担的变化趋势不同，2019年0～4岁儿童伤害死亡率、YLL率、DALY率较1990年下降幅度最大，≥80岁老年人的伤害死亡率有所增加，2019年跌倒死亡率较1990年增加了58.93%。结论 浙江省伤害疾病负担总体呈下降趋势，但跌倒标化死亡率升高、标化YLD率高于全国，且低年龄组和高年龄组疾病负担较重，应继续强化重点人群和重点伤害类型的防制策略，进一步降低浙江省伤害疾病负担。更多还原

【Abstract】 Objective To analyze the injury burden and the change trend of residents in Zhejiang Province from 1990 to 2019,and provide the basis for formulating the preventive strategies of injury. Methods The provincial results of China from the 2019 Global Burden of Disease(GBD 2019) study were used to select the mortality,years of life lost(YLL) rate,years lived with disability(YLD) rate,and disability adjusted life years(DALY) rate from 1990 to 2019;which were age-standardized with GBD 2019 world standard population. The software SAS 9.4 and software Excel 2016 were used to describe the injury burden of residents in Zhejiang Province from 1990 to 2019. The software Joinpoint 4.9.1.0 was used to calculate the average annual percent change(AAPC). Results In 2019,the injury age-standardized mortality was 44.79/105,the age-standardized DALY rate was 2 243.74/105.From 1990 to 2019,the injury age-standardized rates of mortality,YLL and DALY showed the downward trend(AAPC were-2.12%,-3.13% and-2.37%,respectively,P<0.01). And the age-standardized mortality of injury in Zhejiang Province was closed to the national level in the same period. The age-standardized rates of YLL and DALY were lower than the national levels,however,the age-standardized YLD rate was higher than the national level. In 2019,the age-standardized DALY rate and YLL rate of road traffic injury in Zhejiang Province were the first. From 1990 to 2019,the age-standardized mortality rates,YLL rates and DALY rates of injury in males were higher than those in females;but the YLD proportion of DALY in females were higher than those in males. There were differences in trend of injury disease burden among different age groups. The decrease levels of injury mortality,YLL rate and DALY rate in 0-4 years old group from 1990 to 2019 were the greatest;the injury mortality in ≥80 years old group increased;the falls mortality in 2019 increased 58.93%,as compared with 1990. Conclusion The burden of injury disease in Zhejiang Province showed a downward trend,but the falls mortality increased,the level of age-standardized YLD rate was higher than the national level. The disease burden in low age and high age groups was heavier. It should continue to strengthen the prevention and control strategies for key groups and key injury types,and to further reduce the injury disease burden in Zhejiang Province.更多还原