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肝外胆管癌术后辅助放化疗的现况分析

Current Situation of Postoperative Adjuvant Chemoradiotherapy for Extrahepatic Cholangiocarcinoma

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【作者】 杨潇彭慧庄亮

【Author】 YANG Xiao;PENG Hui;ZHUANG Liang;Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology;

【通讯作者】 庄亮;

【机构】 华中科技大学同济医学院同济医院肿瘤科

【摘要】 近年来,肝外胆管癌的发病率逐年递增。因其易侵犯周围肝动脉、肝静脉、门静脉,且根治性切除率低,预后较差,即使早期完成根治术,5年生存率仍不足30%。术后辅助治疗能否改善肝外胆管癌的预后一直是研究的热点及争议点,本文将结合最新的研究进展,讨论肝外胆管癌术后辅助治疗的方案,分析术后辅助治疗对于肝外胆管癌预后的意义。

【Abstract】 In recent years, the incidence of extrahepatic cholangiocarcinoma(ECC) has been increasing annually. As a result of frequently invading adjacent structures, such as hepatic artery, hepatic vein, and portal vein, and low radical resection rate, the prognosis is poor. Even if radical resection is completed early, the 5-year survival rate is still less than 30%. At present, whether postoperative adjuvant therapy can improve the prognosis of ECC remains a research hotspot and a controversial point. This article will combine the latest research results to discuss the plan and status of postoperative adjuvant therapy after ECC, as well as analyze the effect of postoperative adjuvant therapy on ECC.

【基金】 希思科-石药肿瘤研究基金项目(Y-SY201901-0 0 7 4);湖北省自然科学基金(2021CFB331);湖北陈孝平科技发展基金会肝胆胰恶性肿瘤基金(CXPJJH12000001-2020344)~~
  • 【文献出处】 肿瘤防治研究 ,Cancer Research on Prevention and Treatment , 编辑部邮箱 ,2023年01期
  • 【分类号】R735.8
  • 【下载频次】32
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